LAS190792
LAS190792 (AZD8999) is a potent muscarinic antagonist and β2-adrenoceptor agonist with pIC50 8.9, 8.8, 8.8, 9.2, 8.2, 7.5, 9.1, 5.6 for M1, M2, M3, M4, M5, β1, β2, β3, respectively. LAS190792 can be used as a bronchodilator.
For research use only. We do not sell to patients.
- CAS No.: 1347232-69-2
- Formula: C39H43ClN4O9S2
- Molecular Weight:811.36
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Adrenergic Receptor Isoforms
More
Biological Activity
|
β1 adrenoceptor 7.5 (pIC50) |
β2 adrenoceptor 9.1 (pIC50) |
β3 adrenoceptor 5.6 (pIC50) |
mAChR1 8.9 (pIC50) |
mAChR2 8.8 (pIC50) |
mAChR3 8.8 (pIC50) |
mAChR4 9.2 (pIC50) |
mAChR5 8.2 (pIC50) |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 1347232-69-2
-
Molecular Weight 811.36
-
Formula C39H43ClN4O9S2
-
SMILES
COC(C=C(NC(OCCN(C)[C@@H]1CC[C@@H](OC(C(O)(C2=CC=CS2)C3=CC=CS3)=O)CC1)=O)C(Cl)=C4)=C4CNC[C@H](O)C5=CC=C(O)C(N6)=C5C=CC6=O
-
Synonyms
AZD8999
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz