2. Signaling Pathways
  3. Others
  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (11061):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1853R
    Simetryn (Standard)
    Simetryn (Standard) is the analytical standard of Simetryn (HY-B1853). This product is intended for research and analytical applications. Simetryn is a triazine herbicide that exerts teratogenicity. Simetryn inhibits photosynthesis by blocking electron transfer in the chloroplast photosystem II and activates the MEK/Erk signaling pathway. Simetryn triggers vascular and developmental abnormalities in zebrafish and tadpoles, suppresses proliferation, enhances apoptosis, and induces malformations. Simetryn serves as a tool to establish a zebrafish model for studying arteriovenous malformations and related pathogenesis. Simetryn controls paddy weeds and can be used for research on developmental and vascular disorders.
    Simetryn (Standard)
  • HY-12752AR
    Alimemazine hemitartrate (Standard)
    Alimemazine hemitartrate (Standard) is the analytical standard of Alimemazine hemitartrate. This product is intended for research and analytical applications. Alimemazine hemitartrate is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist.
    Alimemazine hemitartrate (Standard)
  • HY-N0805AR
    Alisol B (Standard)
    Alisol B (Standard) is the analytical standard of Alisol B (HY-N0805A). This product is intended for research and analytical applications. Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a Ki of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G1 phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer.
    Alisol B (Standard)
  • HY-133842R
    Acetoacetamide (Standard)
    Acetoacetamide (Standard)
  • HY-78046R
    Ticagrelor impurity 26 (Standard)
    Ticagrelor impurity 26 (Standard) is the analytical standard of Ticagrelor impurity 26 (HY-78046). This product is intended for research and analytical applications.
    Ticagrelor impurity 26 (Standard)
  • HY-W012835R
    4-Methylanisole (Standard)
    4-Methylanisole (Standard) is the analytical standard of 4-Methylanisole (HY-W012835). This product is intended for research and analytical applications. 4-Methylanisole (4-Methoxytoluene) is food flavoring agent and can be naturally found in Ylang Ylang fragrance oil.
    4-Methylanisole (Standard)
  • HY-101928R
    KDM4D-IN-1 (Standard)
    KDM4D-IN-1 (Standard) is the analytical standard of KDM4D-IN-1 (HY-101928). This product is intended for research and analytical applications. KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.
    KDM4D-IN-1 (Standard)
  • HY-W013678R
    H-Glu(OMe)-OH (Standard)
    H-Glu(OMe)-OH (Standard) is the analytical standard of H-Glu(OMe)-OH. This product is intended for research and analytical applications. H-Glu(OMe)-OH is a glutamic acid derivative.
    H-Glu(OMe)-OH (Standard)
  • HY-101523R
    Cdc7-IN-1 (Standard)
    Cdc7-IN-1 (Standard) is the analytical standard of Cdc7-IN-1 (HY-101523). This product is intended for research and analytical applications. Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death.
    Cdc7-IN-1 (Standard)
  • HY-10466R
    Daclatasvir (Standard)
    Daclatasvir (Standard) is the analytical standard of Daclatasvir. This product is intended for research and analytical applications. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively.
    Daclatasvir (Standard)
  • HY-10014R
    R547 (Standard)
    R547 (Standard) is the analytical standard of R547 (HY-10014). This product is intended for research and analytical applications. R547 is a potent, selective and orally active ATP-competitive CDK inhibitor, with Kis of 2 nM, 3 nM and 1 nM for CDK1/cyclin B, CDK2/cyclin E and CDK4/cyclin D1, respectively.
    R547 (Standard)
  • HY-W051610R
    Benzo[d][1,3]dioxole-4-carbaldehyde (Standard)
    Benzo[d][1,3]dioxole-4-carbaldehyde (Standard)
  • HY-101597R
    NVX-207 (Standard)
    NVX-207 (Standard) is the analytical standard of NVX-207 (HY-101597). This product is intended for research and analytical applications. NVX-207, a Betulinic acid-derived anti-cancer compound, shows anti-tumor activity (mean IC50=3.5 μM) against various human and canine cell lines. NVX-207-induced apoptosis is associated with activation of the intrinsic apoptotic pathway via cleavage of caspases -9, -3, -7 and of PARP.
    NVX-207 (Standard)
  • HY-W012340R
    H-HomoArg-OH.HCl (Standard)
    H-HomoArg-OH.HCl is an endogenous metabolite.
    H-HomoArg-OH.HCl (Standard)
  • HY-W013534R
    2-Cyclopentyl-2-hydroxy-2-phenylacetic acid (Standard)
    2-Cyclopentyl-2-hydroxy-2-phenylacetic acid (Standard) is the analytical standard of 2-Cyclopentyl-2-hydroxy-2-phenylacetic acid. This product is intended for research and analytical applications.
    2-Cyclopentyl-2-hydroxy-2-phenylacetic acid (Standard)
  • HY-12015R
    Iniparib (Standard)
    Iniparib (Standard) is the analytical standard of Iniparib. This product is intended for research and analytical applications. Iniparib (BSI-201) is an irreversible inhibitor of PARP1, used in the research of triple negative breast cancer.
    Iniparib (Standard)
  • HY-106150BR
    Eniporide hydrochloride (Standard)
    Eniporide hydrochloride (Standard) is the analytical standard of Eniporide hydrochloride (HY-106150B). This product is intended for research and analytical applications. Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor.
    Eniporide hydrochloride (Standard)
  • HY-109010R
    Poseltinib (Standard)
    Poseltinib (Standard) is the analytical standard of Poseltinib (HY-109010). This product is intended for research and analytical applications. Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine Kinase (BTK) inhibitor. With an IC50 of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis.
    Poseltinib (Standard)
  • HY-Y1125R
    6-Methyluracil (Standard)
    6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo.
    6-Methyluracil (Standard)
  • HY-10191R
    Linsitinib (Standard)
    Linsitinib (Standard) is the analytical standard of Linsitinib. This product is intended for research and analytical applications. Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC50s of 35 and 75 nM, respectively.
    Linsitinib (Standard)