Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
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Reference Standards Related Products (11771)
Related Products (11771)
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Gabexate mesylate (Standard)
0 ImagesCat. No.: HY-B0385RCAS No.: 56974-61-9Synonyms: FOY (Standard)Gabexate (mesylate) (Standard) is the analytical standard of Gabexate (mesylate). This product is intended for research and analytical applications. Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation.
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Hycanthone (Standard)
0 ImagesHycanthone (Standard) is the analytical standard of Hycanthone (HY-B1099). This product is intended for research and analytical applications. Hycanthone is an apurinic/apyrimidinic endonuclease 1 (APE1) inhibitor, DNA intercalator and Antischistosomal agent, with an IC50 of 80 nM against APE1. Hycanthone irreversibly inhibits thymidine incorporation into DNA in adult sensitive *Schistosoma mansoni*, while exerts weak inhibitory effects on uridine and leucine incorporation. Hycanthone reduces influenza virus-induced interferon production. Hycanthone exhibits mutagenic effects in various organisms, shows teratogenicity in mice and rabbits, and induces neoplastic liver lesions in partially hepatectomized mice. Hycanthone can be used in research related to schistosomiasis and cancer.
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Lauflumide (Standard)
0 ImagesCat. No.: HY-111178RCAS No.: 90280-13-0Synonyms: BisfluoroModafinil (Standard); CRL-40940 (Standard); NLS-4 (Standard)Lauflumide (Standard) is the analytical standard of Lauflumide (HY-111178). This product is intended for research and analytical applications. Lauflumide (BisfluoroModafinil) is the common alternative of modafinil. Modafinil is commonly prescribed for the research narcolepsy. Lauflumide has the potential for cognitive enhancing.
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Tizanidine (Standard)
0 ImagesCat. No.: HY-B0194RCAS No.: 51322-75-9Tizanidine (Standard) is the analytical standard of Tizanidine (HY-B0194). This product is intended for research and analytical applications. Tizanidine, a skeletal muscle relaxant, is an orally effective central α2-adrenoceptor agonist (IC50 = 6.9 nmol). Tizanidine primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine can inhibit the proliferation, migration, and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine can be used to treat spasticity caused by diseases such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI).
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Ascr#3 (Standard)
0 ImagesCat. No.: HY-N6977RCAS No.: 946524-26-1Ascr#3 (Standard) is the analytical standard of Ascr#3 (HY-N6977). This product is intended for research and analytical applications. Ascr#3 is a type of pheromone found in the beautiful nematode, and when mixed with ascr#2, it can act as a male attractant and also induce the formation of dauer (the dormant larval stage). Ascr#3 can counteract the effects caused by male-enriched Ascr#10.
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3-Hydroxycapric acid (Standard)
0 ImagesCat. No.: HY-113057RCAS No.: 14292-26-3Trihexyphenidyl (hydrochloride) (Standard) is the analytical standard of Trihexyphenidyl (hydrochloride). This product is intended for research and analytical applications. Trihexyphenidyl hydrochloride is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl hydrochloride shows anticholinergic activity, and can be used for Parkinson syndrome or dystonia research.
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Pramocaine hydrochloride (Standard)
0 ImagesPramocaine (Pramoxine) hydrochloride (Standard) is the analytical standard of Pramocaine hydrochloride (HY-B1319). This product is intended for research and analytical applications. Pramocaine hydrochloride is a topical surface anesthetic and antipruritic agent. Pramocaine hydrochloride reversibly inhibits voltage-gated sodium channel, reduces transmembrane permeability of sodium ions, stabilizes cell membranes, prevents depolarization, blocks action potential conduction, and inhibits peripheral slow C-fiber pathways associated with pain, pruritus and thermoception. Pramocaine hydrochloride can be used in research related to chronic pruritus, renal pruritus, atopic dermatitis, xerotic pruritus, uremic pruritus, and cutaneous hyperalgesia/pain.
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Valbilan (Standard)
0 ImagesCat. No.: HY-106535RCAS No.: 3102-00-9Synonyms: Febuprol (Standard)
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L-Canavanine sulfate (Standard)
0 ImagesL-Canavanine (sulfate) (Standard) is the analytical standard of L-Canavanine (sulfate). This product is intended for research and analytical applications. L-Canavanine sulfate is a selective inhibitor of inducible NO synthase.
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Naxagolide (Standard)
0 ImagesSynonyms: (+)-PHNO (Standard); Dopazinol (Standard)Naxagolide (Standard) is the analytical standard of Naxagolide. This product is intended for research and analytical applications. Naxagolide ((+)-PHNO; Dopazinol) is a potent dopamine D2 (Dopamine Receptor) agonist. Naxagolide has the potential for the research of parkinson's disease (PD).
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Olorofim (Standard)
0 ImagesSynonyms: F901318 (Standard)Olorofim (Standard) is the analytical standard of Olorofim (HY-104029). This product is intended for research and analytical applications. Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp..
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4-Isobutylbenzoic acid (Standard)
0 Images4-Isobutylbenzoic acid (Standard) is the analytical standard of 4-Isobutylbenzoic acid. This product is intended for research and analytical applications. 4-Isobutylbenzoic acid is an intermediate in the synthesis of compounds.
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MK-2206 (Standard)
0 ImagesCat. No.: HY-108232RCAS No.: 1032349-77-1MK-2206 (Standard) is the analytical standard of MK-2206 (HY-108232). This product is intended for research and analytical applications. MK-2206 is an orally active, highly potent and selective allosteric Akt inhibitor, with IC50s of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. Many breast cancer cell lines, and PIK3CA-mutant and cell lines with PTEN loss are sensitive to MK-2206. MK-2206 has anticancer activities.
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EED226 (Standard)
0 ImagesEED226 (Standard) is the analytical standard of EED226 (HY-101117). This product is intended for research and analytical applications. EED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model. EED226 is a potent, selective, and orally bioavailable EED inhibitor. EED226 inhibits PRC2 with an IC50 of 23.4 nM when the H3K27me0 peptide is used as a substrate in the in vitro enzymatic assays.
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GSK-3685032 (Standard)
0 ImagesCat. No.: HY-139664RCAS No.: 2170137-61-6GSK-3685032 (Standard) is the analytical standard of GSK-3685032 (HY-139664). This product is intended for research and analytical applications. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition.
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WT-161 (Standard)
0 ImagesCat. No.: HY-100871RCAS No.: 1206731-57-8WT-161 (Standard) is the analytical standard of WT-161 (HY-100871). This product is intended for research and analytical applications. WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM. WT-161 also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2).
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Gemcitabine monophosphate (Standard)
0 ImagesCat. No.: HY-108932RCAS No.: 116371-67-6Synonyms: Gemcitabine 5′-phosphate (Standard)Gemcitabine monophosphate (Standard) is the analytical standard of Gemcitabine monophosphate (HY-108932). This product is intended for research and analytical applications. Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles.
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LTURM34 (Standard)
0 ImagesCat. No.: HY-101667RCAS No.: 1879887-96-3LTURM34 (Standard) is the analytical standard of LTURM34 (HY-101667). This product is intended for research and analytical applications. LTURM34 is a specific DNA-PK inhibitor (IC50=34 nM). LTURM34 exhibits 170-fold selectivity for DNA-PK over PI3K. LTURM34 shows potent antiproliferative activity in a wide range of tumor cell lines.
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HCH6-1 (Standard)
0 ImagesCat. No.: HY-101283RCAS No.: 1435265-06-7HCH6-1 (Standard) is the analytical standard of HCH6-1 (HY-101283). This product is intended for research and analytical applications. HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases.
