2. Metabolic Enzyme/Protease Others
  3. ACSL Family Drug Derivative
  4. ACSL5-IN-2

ACSL5-IN-2 (Compound B) is an Acyl CoA synthetase 5 (ACSL5) inhibitor. ACSL5-IN-2 can block the conversion of long-chain fatty acids (such as palmitic acid and oleic acid) into acyl-CoA, and intervene in the fatty acid metabolism pathway. ACSL5-IN-2 can inhibit cancer cells growth. ACSL5-IN-2 can be used for the research of cancer and metabolic disease, such as colon cancer and dysfunction-associated Steatohepatitis.

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ACSL5-IN-2

ACSL5-IN-2 Estructura química

No. CAS : 3098297-74-3

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg   Obtener un presupuesto  
200 mg   Obtener un presupuesto  

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ACSL5-IN-2 Related Antibodies

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Descripciòn

ACSL5-IN-2 (Compound B) is an Acyl CoA synthetase 5 (ACSL5) inhibitor. ACSL5-IN-2 can block the conversion of long-chain fatty acids (such as palmitic acid and oleic acid) into acyl-CoA, and intervene in the fatty acid metabolism pathway. ACSL5-IN-2 can inhibit cancer cells growth. ACSL5-IN-2 can be used for the research of cancer and metabolic disease, such as colon cancer and dysfunction-associated Steatohepatitis[1].

IC50 & Target

ACSL5

 

Peso molecular

589.65

Fòrmula

C29H33F2N3O6S
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

CC[C@@H](OC1=C(F)C(F)=C(C(NS(C2=CC=C(OCCN(C)C)C=C2)(=O)=O)=O)C=C1)C3=CC=C(OCC4CC4)C=N3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 25 mg/mL (42.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6959 mL 8.4796 mL 16.9592 mL
5 mM 0.3392 mL 1.6959 mL 3.3918 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.51%

SDS (251 KB)

COA (251 KB) HNMR (340 KB) RP-HPLC (255 KB) MS (68 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6959 mL 8.4796 mL 16.9592 mL 42.3980 mL
5 mM 0.3392 mL 1.6959 mL 3.3918 mL 8.4796 mL
10 mM 0.1696 mL 0.8480 mL 1.6959 mL 4.2398 mL
15 mM 0.1131 mL 0.5653 mL 1.1306 mL 2.8265 mL
20 mM 0.0848 mL 0.4240 mL 0.8480 mL 2.1199 mL
25 mM 0.0678 mL 0.3392 mL 0.6784 mL 1.6959 mL
30 mM 0.0565 mL 0.2827 mL 0.5653 mL 1.4133 mL
40 mM 0.0424 mL 0.2120 mL 0.4240 mL 1.0600 mL
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ACSL5-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ACSL5-IN-23098297-74-3ACSL FamilyDrug DerivativeDrug derivativeAcyl CoA synthetaseACSL5palmitic acidoleic acidacyl-CoAcancerdysfunction-associated SteatohepatitisInhibitorinhibitorinhibit

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Nombre del producto:
ACSL5-IN-2
Cat. No.:
HY-177705
Cantidad:
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SAFETY DATA SHEET (SDS)

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