2. Anti-infection
  3. HIV
  4. Ainuovirine

Ainuovirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI). Ainuovirine inhibits HIV replication by non-competitively binding to HIV reverse transcriptase and blocking the reverse transcription process of viral RNA. Ainuovirine can be used for human immunodeficiency virus (HIV) type 1 infection.

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Ainuovirine

Ainuovirine Estructura química

No. CAS : 1097628-00-6

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1 mg Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
5 mg Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
10 mg Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
25 mg Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
50 mg Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
100 mg   Obtener un presupuesto  
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Ainuovirine Related Antibodies

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Descripciòn

Ainuovirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI). Ainuovirine inhibits HIV replication by non-competitively binding to HIV reverse transcriptase and blocking the reverse transcription process of viral RNA. Ainuovirine can be used for human immunodeficiency virus (HIV) type 1 infection[1].

Cellular Effect
Cell Line Type Value Description References
MT2 EC50
6.1 nM
Compound: 10b
Antiviral activity against wild type HIV1 infected in human MT2 cells
Antiviral activity against wild type HIV1 infected in human MT2 cells
[PMID: 20138513]
MT2 EC50
6.4 nM
Compound: 10b
Antiviral activity against NNRTI-resistant HIV1 harboring reverse transcriptase K103N mutant infected in human MT2 cells
Antiviral activity against NNRTI-resistant HIV1 harboring reverse transcriptase K103N mutant infected in human MT2 cells
[PMID: 20138513]
MT2 EC50
9.6 nM
Compound: 10b
Antiviral activity against HIV1 harboring reverse transcriptase Y181C mutant infected in human MT2 cells
Antiviral activity against HIV1 harboring reverse transcriptase Y181C mutant infected in human MT2 cells
[PMID: 20138513]
Ensayo clínico
Peso molecular

325.36

Fòrmula

C18H19N3O3
No. CAS
SMILES

N#CC1=CC(C)=CC(C(C2=C(C(C)C)C(NC(N2CC)=O)=O)=O)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
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Ainuovirine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ainuovirine1097628-00-6HIVHuman immunodeficiency virusHIV proteasemicrobiologyvirologyproteasesnoncompetitive inhibitionInhibitorinhibitorinhibit

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Nombre del producto:
Ainuovirine
Cat. No.:
HY-139158
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