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Aluminum potassium sulfate  (Synonyms: Potassium alum)

製品番号: HY-W134301 純度: 99.6%
COA 取扱説明書 Technical Support

Aluminum potassium sulfate (Potassium alum) is an egg white adjuvant. Aluminum potassium sulfate acts as a mordant to help dyes bind to tissue components, enhancing the staining effect and stability during staining. Aluminum potassium sulfate can induce allergic reactions in mice. Aluminum potassium sulfate can be used in research for bacterial and tissue staining.

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Aluminum potassium sulfate

Aluminum potassium sulfate 構造式

CAS 番号 : 10043-67-1

容量 価格（税別） 在庫状況 数量
5 g $32 在庫あり
10 g $50 在庫あり
25 g $85 在庫あり
50 g $120 在庫あり
> 100 g   お問い合わせ  

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Aluminum potassium sulfate 関連抗体

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製品説明

Aluminum potassium sulfate (Potassium alum) is an egg white adjuvant. Aluminum potassium sulfate acts as a mordant to help dyes bind to tissue components, enhancing the staining effect and stability during staining. Aluminum potassium sulfate can induce allergic reactions in mice. Aluminum potassium sulfate can be used in research for bacterial and tissue staining[1][2][3][4].

体外実験

Aluminum potassium sulfate (4 h) irreversibly inhibits α-amylase (70% reduction), protease (51% reduction), and lipase (31% reduction) activities in midgut extracts of adult Periplaneta americana, with greater inhibitory effects observed in females than males[1].
Aluminum potassium sulfate can be used as an adjuvant of ovalbumin to induce anaphylaxis in mice.[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aluminum potassium sulfate 関連抗体
体内実験

Formalized Vibrio anguillarum bacterin adjuvanted with 2.5% Aluminum potassium sulfate (50-100 μL; i.p.) causes a significant reduction in growth, severe chronic peritonitis and organ damage in rainbow trout[3].
Formalized Vibrio anguillarum bacterin adjuvanted with 2.5% Aluminum potassium sulfate (100-200 μL; i.p.) causes minimal mortality, a significant reduction in growth, mild to moderate organ damage in rainbow trout[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Salmo gairdneri Richardson (approximately 3 cm length, mean weight 1.5 g)[3]
Dosage: 50; 100 μl (adjuvanted with 2.5% Aluminum potassium sulfate)
Administration: i.p.
Result: Reached 67% cumulative mortality at 48 days post-vaccination for the 50 μl adjuvanted dose.
Reached 74% cumulative mortality at 48 days post-vaccination for the 100 μl adjuvanted dose.
Achieved 231% weight increase over six weeks for the 50 μl adjuvanted dose.
Caused severe reactive peritonitis, inflammatory oedema of visceral peritoneum, macrophage infiltration and adjuvant deposition in serosa of ovary, liver, and pancreas, progressive focal degeneration of pancreatic acini, granulomata formation, fibroblast proliferation with collagen deposition, splenic and renal haemopoietic tissue depletion, occasional subcapsular hepatic necrosis, and heavy sequestration of alum into hepatocytes.
Showed no significant additional protection against Vibrio anguillarum challenge compared to non-adjuvanted vaccine.
Animal Model: Salmo gairdneri Richardson (20 cm length, mean weight 100 g-156 g)[3]
Dosage: 100; 200 μl (adjuvanted with 2.5% Aluminum potassium sulfate)
Administration: i.p.
Result: Reached 5% cumulative mortality at 48 days post-vaccination for the 100 μl adjuvanted dose.
Reached 6% cumulative mortality at 48 days post-vaccination for the 200 μl adjuvanted dose.
Achieved 53% weight increase over six weeks for the 100 μl adjuvanted dose.
Achieved 26% weight increase over six weeks for the 200 μl adjuvanted dose.
Caused peritoneal oedema, macrophage infiltration, distortion of pancreatic acini, focal hepatic necrosis, severe focal necrosis of renal haemopoietic tissue, sequestration of alum into hepatocytes, pancreatic tissue fibrosis, organizing focal necrosis of liver and kidney, increased macrophage activity in peritoneal tissues, reduction in splenic white pulp, and gonad damage with fibrosed tissue contraction by one month post-injection.
Showed no significant additional protection against Vibrio anguillarum challenge compared to non-adjuvanted vaccine.
分子量

258.21

分子式

KAl(SO4)2
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

[K][Al](S(=O)(O[O])=O)S(=O)(O[O])=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Store at room temperature, keep dry and cool

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature, keep dry and cool)
溶剤 & 溶解度
体外: 

H2O : 2 mg/mL (7.75 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8728 mL 19.3641 mL 38.7282 mL
5 mM 0.7746 mL 3.8728 mL 7.7456 mL
10 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

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体積 （終了）

V2

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  Saline

    Solubility: 5 mg/mL (19.36 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.6%

COA (248 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.8728 mL 19.3641 mL 38.7282 mL 96.8204 mL
5 mM 0.7746 mL 3.8728 mL 7.7456 mL 19.3641 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Aluminum potassium sulfate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aluminum potassium10043-67-1Potassium alumBiochemical Assay Reagentsα-amylaserainbow troutPeriplaneta americanaallergic asthmaeczemaproteaselipaseVibrio anguillarumrhinitisInhibitorinhibitorinhibit

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