Potassiumalum, for cell culture (Synonyms: Aluminum potassium sulfate dodecahydrate, for cell culture)

Cat. No.: HY-B2241A Purity: 98.01%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Potassiumalum, for cell culture (Aluminum potassium sulfate dodecahydrate, for cell culture) is an egg white adjuvant. Potassiumalum, for cell culture acts as a mordant to help dyes bind to tissue components, enhancing the staining effect and stability during staining. Potassiumalum, for cell culture can induce allergic reactions in mice. Potassium alum, for cell culture can be used in research for bacterial and tissue staining.

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Potassiumalum, for cell culture 화학구조

CAS No. : 7784-24-9

사이즈	재고	수량
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	해외재고보유	Estimated Time of Arrival: December 31
25 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	해외재고보유	Estimated Time of Arrival: December 31
> 100 g	견적 받기

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This product is a controlled substance and not for sale in your territory.

Other Forms of Potassiumalum, for cell culture:

Aluminum potassium sulfate In-stock

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

In Vitro

Potassiumalum (4 h) irreversibly inhibits α-amylase (70% reduction), protease (51% reduction), and lipase (31% reduction) activities in midgut extracts of adult Periplaneta americana, with greater inhibitory effects observed in females than males^[1].
Potassiumalum can be used as an adjuvant of ovalbumin to induce anaphylaxis in mice.^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Formalized Vibrio anguillarum bacterin adjuvanted with 2.5% Potassiumalum (50-100 μL; i.p.) causes a significant reduction in growth, severe chronic peritonitis and organ damage in rainbow trout^[3].
Formalized Vibrio anguillarum bacterin adjuvanted with 2.5% Potassiumalum (100-200 μL; i.p.) causes minimal mortality, a significant reduction in growth, mild to moderate organ damage in rainbow trout^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Salmo gairdneri Richardson (approximately 3 cm length, mean weight 1.5 g)^[3]
Dosage:	50; 100 μl (adjuvanted with 2.5% Potassiumalum)
Administration:	i.p.
Result:	Reached 67% cumulative mortality at 48 days post-vaccination for the 50 μl adjuvanted dose. Reached 74% cumulative mortality at 48 days post-vaccination for the 100 μl adjuvanted dose. Achieved 231% weight increase over six weeks for the 50 μl adjuvanted dose. Caused severe reactive peritonitis, inflammatory oedema of visceral peritoneum, macrophage infiltration and adjuvant deposition in serosa of ovary, liver, and pancreas, progressive focal degeneration of pancreatic acini, granulomata formation, fibroblast proliferation with collagen deposition, splenic and renal haemopoietic tissue depletion, occasional subcapsular hepatic necrosis, and heavy sequestration of alum into hepatocytes. Showed no significant additional protection against Vibrio anguillarum challenge compared to non-adjuvanted vaccine.

Animal Model:	Salmo gairdneri Richardson (20 cm length, mean weight 100 g-156 g)^[3]
Dosage:	100; 200 μl (adjuvanted with 2.5% Potassiumalum)
Administration:	i.p.
Result:	Reached 5% cumulative mortality at 48 days post-vaccination for the 100 μl adjuvanted dose. Reached 6% cumulative mortality at 48 days post-vaccination for the 200 μl adjuvanted dose. Achieved 53% weight increase over six weeks for the 100 μl adjuvanted dose. Achieved 26% weight increase over six weeks for the 200 μl adjuvanted dose. Caused peritoneal oedema, macrophage infiltration, distortion of pancreatic acini, focal hepatic necrosis, severe focal necrosis of renal haemopoietic tissue, sequestration of alum into hepatocytes, pancreatic tissue fibrosis, organizing focal necrosis of liver and kidney, increased macrophage activity in peritoneal tissues, reduction in splenic white pulp, and gonad damage with fibrosed tissue contraction by one month post-injection. Showed no significant additional protection against Vibrio anguillarum challenge compared to non-adjuvanted vaccine.

분자량

474.39

화학식

KAl(SO₄)₂·12H₂O

CAS No.

7784-24-9

Appearance

Solid

Color

White to off-white

SMILES

[KAl(SO4)2 ?12H2O]

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : 200 mg/mL (421.59 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1080 mL	10.5399 mL	21.0797 mL
5 mM	0.4216 mL	2.1080 mL	4.2159 mL
10 mM	0.2108 mL	1.0540 mL	2.1080 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 98.01%

Select Batch:

Data Sheet (275 KB) SDS (393 KB)

COA (243 KB)

Handling Instructions (2659 KB)

References

[1]. Salama EM, et al. A Novel Use for Potassium Alum as Controlling Agent Against Periplaneta americana (Dictyoptera: Blattidae). J Econ Entomol. 2015;108(6):2620-2629. [Content Brief]

[2]. Sevki C, et al. Reduction of house-dust mite allergen concentrations in carpets by aluminium potassium sulfate dodecahydrate (alum). Allergy Asthma Proc. 2006;27(5):350-353. [Content Brief]

[3]. Horne M T, et al. The effects of the use of potassium alum adjuvant in vaccines against vibriosis in rainbow trout, Salmo gairdneri Richardson. J. Fish Dis. 1984, 7, 91-99.

[4]. Jun Ren, et al. Selective flotation of bastnaesite from monazite in rare earth concentrates using potassium alum as depressant. June 2000. International Journal of Mineral Processing. 59(3):237-245.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.1080 mL	10.5399 mL	21.0797 mL	52.6993 mL
	5 mM	0.4216 mL	2.1080 mL	4.2159 mL	10.5399 mL
	10 mM	0.2108 mL	1.0540 mL	2.1080 mL	5.2699 mL
	15 mM	0.1405 mL	0.7027 mL	1.4053 mL	3.5133 mL
	20 mM	0.1054 mL	0.5270 mL	1.0540 mL	2.6350 mL
	25 mM	0.0843 mL	0.4216 mL	0.8432 mL	2.1080 mL
	30 mM	0.0703 mL	0.3513 mL	0.7027 mL	1.7566 mL
	40 mM	0.0527 mL	0.2635 mL	0.5270 mL	1.3175 mL
	50 mM	0.0422 mL	0.2108 mL	0.4216 mL	1.0540 mL
	60 mM	0.0351 mL	0.1757 mL	0.3513 mL	0.8783 mL
	80 mM	0.0263 mL	0.1317 mL	0.2635 mL	0.6587 mL
	100 mM	0.0211 mL	0.1054 mL	0.2108 mL	0.5270 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Potassiumalum, for cell culture Related Classifications

Inflammation/Immunology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Potassiumalum, for cell culture7784-24-9Aluminum potassium sulfate dodecahydrate, for cell cultureBiochemical Assay Reagentsα-amylaserainbow trout*Periplaneta americana*allergic asthmaeczemaproteaseDer p 1lipaseVibrio anguillarumrhinitisInhibitorinhibitorinhibit

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Potassiumalum, for cell culture (Synonyms: Aluminum potassium sulfate dodecahydrate, for cell culture)

Other Forms of Potassiumalum, for cell culture:

Potassiumalum, for cell culture Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

순도&문서

References

고객리뷰

Potassiumalum, for cell culture Related Antibodies

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