2. Inhibitorische Antikörper
  3. In Vivo Antibodies
  4. Anti-Mouse CD200 Antibody (OX-90)

Anti-Mouse CD200 Antibody (OX-90) 

Art. -Nr.: HY-P990285 Reinheit: 95.00%
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Anti-Mouse CD200 Antibody (OX-90) is an anti-mouse CD200 IgG2a monoclonal antibody. Anti-Mouse CD200 Antibody (OX-90) can reduce immune cell infiltration and T cell function by blocking CD200. Anti-Mouse CD200 Antibody (OX-90) can be used for research on immunology.

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Anti-Mouse CD200 Antibody (OX-90)

Anti-Mouse CD200 Antibody (OX-90) Chemische Struktur

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Beschreibung

Anti-Mouse CD200 Antibody (OX-90) is an anti-mouse CD200 IgG2a monoclonal antibody. Anti-Mouse CD200 Antibody (OX-90) can reduce immune cell infiltration and T cell function by blocking CD200. Anti-Mouse CD200 Antibody (OX-90) can be used for research on immunology[1][2].

Isotype

Rat IgG2a kappa
Recommend Isotype Controls
Species Reactivity

Mouse
IC50 & Target

CD200
In Vivo

Anti-Mouse CD200 Antibody (OX-90) (250 μg, i.p., once every 3 days, from day 7 to day 18) reduces immune cell infiltration and T cell function in tumor immune microenvironment (TIME) in C57BL/6 mice bearing Yumm1.7 tumors[1].
Anti-Mouse CD200 Antibody (OX-90) (200 μg, i.v., on day 3, 6, 9,12) can weaken the therapeutic effect of anti-PD-L1 mAb in female C57BL/6 mice bearing MC38 or EG7 tumors[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 5×105 Yumm1.7 cells injected C57BL/6 mice[1]
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.), once every 3 days, from day 7 to day 18
Result: Reduced immune cells in tumors and upregulated CCL8 expression.
Animal Model: 5×105 MC38 or EG7 cells injected female C57BL/6 mice (6-8 weeks)[2]
Dosage: 200 μg
Administration: Intravenous injection (i.v.), on day 3, 6, 9,12
Result: Weakened the therapeutic effect of anti-PD-L1 mAb.
Gene ID

17470  [NCBI]

Accession
Application

in vivo CD200 blockade; in vitro CD200 blockade; Immunohistochemistry (frozen); Immunofluorescenc
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molekulargewicht

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Mouse CD200 Antibody (OX-90)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Anti-Mouse CD200 Antibody (OX-90) Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD200 Antibody (OX-90)OthersCD200T cellMC38EG7Yumm1.7Inhibitorinhibitorinhibit

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