GABA Transporter 1 Antibody (YA1795)

Cat. No.: HY-P82050: Data Sheet COA
SDS
User Guide for Antibodies
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Technical Support

GABA Transporter 1 Antibody (YA1795) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GABA Transporter 1.

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사이즈	재고	수량
20 μL	해외재고보유	Estimated Time of Arrival: December 31
50 μL	해외재고보유	Estimated Time of Arrival: December 31
100 μL	해외재고보유	Estimated Time of Arrival: December 31
250 μL	견적 받기

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GABA Transporter 1 Antibody (YA1795) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

GABA Transporter 1 Antibody (YA1795) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GABA Transporter 1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

분자량

Predicted band size: 67 kDa;

Observed band size: 67 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P30531

Gene ID

6529 [NCBI]

Immunogen

A synthesized peptide derived from human SLC6A1 / GAT1 aa1-50/599.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Mediates transport of gamma-aminobutyric acid (GABA) together with sodium and cH2O2ide and is responsible for the reuptake of GABA from the synapse (PubMed:30132828). The translocation of GABA, however, may also occur in the reverse direction leading to the release of GABA (By similarity). The direction and magnitude of GABA transport is a consequence of the prevailing thermodynamic conditions, determined by membrane potential and the intracellular and extracellular concentrations of Na(+), Cl(-) and GABA (By similarity). Can also mediate sodium- and cH2O2ide-dependent transport of hypotaurine but to a much lower extent as compared to GABA (By similarity)

Subcellular Localization：Cell membrane; Multi-pass membrane protein; Presynapse

Subunit：Interacts (via PDZ domain-binding motif) with PALS1; interaction increases SLC6A1-mediated GABA uptake

Database

Entrez Gene: 6529 Human ; 232333 Mouse ; 79212 Rat

SwissProt: P30531 Human ; P31648 Mouse ; P23978 Rat

OMIM: 616421 Human

Research Field

Neuroscience

Synonyms

GABATHG; GABATR; GABT1; GAT1; Slc6a1

각종 서류

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

GABA Transporter 1 Antibody (YA1795) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GABA Transporter 1 Antibody (YA1795)

GABA Transporter 1 Antibody (YA1795) Featured Recommendations:

Product Detail

Background

제품 설명

GABA Transporter 1 Antibody (YA1795) Related Classifications

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SAFETY DATA SHEET (SDS)

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