GABA Transporter 1 Antibody (YA1795)

製品番号: HY-P82050: データシート SDS COA User Guide for Antibodies
FAQs
Technical Support

GABA Transporter 1 Antibody (YA1795) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GABA Transporter 1.

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容量	価格（税別）	在庫状況	数量
20 μL	$146	在庫あり	Estimated Time of Arrival: December 31
50 μL	$222	在庫あり	Estimated Time of Arrival: December 31
100 μL	$360	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

GABA Transporter 1 Antibody (YA1795) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GABA Transporter 1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

分子量

Predicted band size: 67 kDa;

Observed band size: 67 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P30531

Gene ID

6529 [NCBI]

Immunogen

A synthesized peptide derived from human SLC6A1 / GAT1 aa1-50/599.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	純度	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Mediates transport of gamma-aminobutyric acid (GABA) together with sodium and cH2O2ide and is responsible for the reuptake of GABA from the synapse (PubMed:30132828). The translocation of GABA, however, may also occur in the reverse direction leading to the release of GABA (By similarity). The direction and magnitude of GABA transport is a consequence of the prevailing thermodynamic conditions, determined by membrane potential and the intracellular and extracellular concentrations of Na(+), Cl(-) and GABA (By similarity). Can also mediate sodium- and cH2O2ide-dependent transport of hypotaurine but to a much lower extent as compared to GABA (By similarity)

Subcellular Localization：Cell membrane; Multi-pass membrane protein; Presynapse

Subunit：Interacts (via PDZ domain-binding motif) with PALS1; interaction increases SLC6A1-mediated GABA uptake

Database

Entrez Gene: 6529 Human ; 232333 Mouse ; 79212 Rat

SwissProt: P30531 Human ; P31648 Mouse ; P23978 Rat

OMIM: 616421 Human

Research Field

Neuroscience

Synonyms

GABATHG; GABATR; GABT1; GAT1; Slc6a1

ドキュメンテーション

Select Batch:

データシート (231 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)