BNP Antibody (YA1000)

製品番号: HY-P81288A: データシート User Guide for Antibodies
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BNP Antibody (YA1000) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BNP.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況	数量
20 μL	$146	Get quote 3 - 4 Weeks 2 - 3 Weeks 4 - 5 Weeks 3 - 4 weeks	Estimated Time of Arrival: December 31
50 μL	$222	Get quote 3 - 4 Weeks 2 - 3 Weeks 4 - 5 Weeks 3 - 4 weeks	Estimated Time of Arrival: December 31
100 μL	$360	Get quote 3 - 4 Weeks 2 - 3 Weeks 4 - 5 Weeks 3 - 4 weeks	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

Synthetic products have potential research and development risk.

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* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

BNP Antibody (YA1000) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BNP.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 15 kDa;

Observed band size: 30 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P16860

Gene ID

4879 [NCBI]

Immunogen

Synthetic peptide derived from human NT-proBNP.

Application &
Dilution Ratio

Application	Dilution Ratio
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	純度	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (PubMed:1672777, PubMed:17372040, PubMed:1914098, PubMed:9458824). May also function as a paracrine antifibrotic factor in the heart (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses (PubMed:1672777, PubMed:17349887, PubMed:17372040, PubMed:21098034, PubMed:25339504, PubMed:9458824). Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion (PubMed:1914098, PubMed:9458824). Binds the clearance receptor NPR3 (PubMed:16870210); May affect cardio-renal homeostasis (PubMed:17372040). Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32 (PubMed:17372040); May have a role in cardio-renal homeostasis (PubMed:17372040). Able to promote the production of cGMP (PubMed:17372040)

Subcellular Localization：Secreted; Secreted; Secreted; Secreted

Expression：
Tissue_specificity:Protein levels were detected in the atria (PubMed: 2136732, PubMed: 2138890) . Protein levels were detected in the distal convoluted tubule cells of the kidney (PubMed: 9794555) .

Database

Entrez Gene: 4879 Human

SwissProt: P16860 Human

OMIM: 600295 Human

Research Field

Neuroscience

Synonyms

NPPB; Natriuretic peptides B; Gamma-brain natriuretic peptide

ドキュメンテーション

User Guide for Antibodies (1077 KB)