2. Anti-infection
  3. Enterovirus
  4. Antiviral agent 23

Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection.

Para uso exclusivo en investigación. No vendemos a pacientes.

Antiviral agent 23

Antiviral agent 23 Estructura química

No. CAS : 35940-03-5

Tamaño Stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  
250 mg   Obtener un presupuesto  

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Antiviral agent 23 Related Antibodies

Top Publications Citing Use of Products

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection[1].

Cellular Effect
Cell Line Type Value Description References
B16 IC50
> 166.7 μM
Compound: 12
Antitumor activity against mouse B16 cells after 72 hrs by Calcein AM assay
Antitumor activity against mouse B16 cells after 72 hrs by Calcein AM assay
[PMID: 17418578]
CCRF-CEM IC50
19.1 μM
Compound: 12
Antitumor activity against human CEM cells after 72 hrs by Calcein AM assay
Antitumor activity against human CEM cells after 72 hrs by Calcein AM assay
[PMID: 17418578]
G-361 IC50
> 166.7 μM
Compound: 12
Antitumor activity against human G361 cells after 72 hrs by Calcein AM assay
Antitumor activity against human G361 cells after 72 hrs by Calcein AM assay
[PMID: 17418578]
HL-60 IC50
6.4 μM
Compound: 12
Antitumor activity against human HL60 cells after 72 hrs by Calcein AM assay
Antitumor activity against human HL60 cells after 72 hrs by Calcein AM assay
[PMID: 17418578]
HOS IC50
> 166.7 μM
Compound: 12
Antitumor activity against human HOS cells after 72 hrs by Calcein AM assay
Antitumor activity against human HOS cells after 72 hrs by Calcein AM assay
[PMID: 17418578]
HeLa CC50
> 100 μM
Compound: 11b
Cytotoxicity against human HeLa cells by MTS assay
Cytotoxicity against human HeLa cells by MTS assay
[PMID: 36455356]
K562 IC50
> 166.7 μM
Compound: 12
Antitumor activity against human K562 cells after 72 hrs by Calcein AM assay
Antitumor activity against human K562 cells after 72 hrs by Calcein AM assay
[PMID: 17418578]
NIH3T3 IC50
> 166.7 μM
Compound: 12
Cytotoxicity against mouse NIH 3T3 cells after 72 hrs by Calcein AM assay
Cytotoxicity against mouse NIH 3T3 cells after 72 hrs by Calcein AM assay
[PMID: 17418578]
RD CC50
> 100 μM
Compound: 11b
Cytotoxicity against human RD cells by MTS assay
Cytotoxicity against human RD cells by MTS assay
[PMID: 36455356]
Vero CC50
> 100 μM
Compound: 11b
Cytotoxicity against african green monkey Vero cells by MTS assay
Cytotoxicity against african green monkey Vero cells by MTS assay
[PMID: 36455356]
Vero C1008 CC50
> 100 μM
Compound: 11b
Cytotoxicity against african green monkey Vero E6 cells by MTS assay
Cytotoxicity against african green monkey Vero E6 cells by MTS assay
[PMID: 36455356]
In Vitro

Antiviral agent 23 (0-100 μM) inhibits CVA21 and EV68 replication in HeLa cells with EC50 values of 36.4 and 8.9 μM, respectively[1].
Antiviral agent 23 (100 μM) inhibits the enzymatic activity of METTL3/METTL14 of 74.45%[1].
Antiviral agent 23 (0-100 μM) shows antiviral effect to EV71 and inhibits the replication of the EV71 strain BrCr in RD cells with an EC50 value of 94 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antiviral agent 23 Related Antibodies
Peso molecular

371.39

Fòrmula

C18H21N5O4
No. CAS
SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN=C3NCC4=CC=CC(C)=C4)=C3N=C2)O1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Antiviral agent 23 Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiviral agent 2335940-03-5Antiviral agent23Antiviral agent-23EnterovirusRhinovirusHRVHRVsHEVHEVsnucleoside analogueinfectionEV71CVA21EV68HeLaInhibitorinhibitorinhibit

Productos vistos recientemente:

Consulta en línea

Your information is safe with us. * Required Fields.

Nombre del producto

  

Requested Quantity *

Nombre del solicitante *

 

Saludo

Direcciòn del E-mail *

 

Número de teléfono *

Department

 

Nombre de la Organizaciòn *

City

Provincia

Country or Region *

      

Observaciones

Consulta para venta a granel

Inquiry Information

Nombre del producto:
Antiviral agent 23
Cat. No.:
HY-151924
Cantidad:
MCE Japan Authorized Agent:

Revisión del cliente

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Nombre del producto

  

Lot #

Nombre del solicitante *

 

Direcciòn del E-mail *

Número de teléfono

 

Department *

Nombre de la Organizaciòn *

 

Country or Region *

Observaciones

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.