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Results for "

EV71

" in MedChemExpress (MCE) Product Catalog:

22

Inhibitors & Agonists

2

Fluorescent Dye

7

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W016407
    Methyl 3,4-dihydroxyphenylacetate

    		Enterovirus Infection
    Methyl 3,4-dihydroxyphenylacetate is a potent enterovirus 71 (EV71) infection inhibitor. Methyl 3,4-dihydroxyphenylacetate inhibits EV71 replication in rhabdomyosarcoma (RD) cells .
    Methyl 3,4-dihydroxyphenylacetate
  • HY-120900
    AN-12-H5

    		Enterovirus Infection Inflammation/Immunology
    AN-12-H5, an antienterovirus compound, targets the replication processes of PV and enterovirus 71 (EV71) .
    AN-12-H5
  • HY-128382
    Brilliant Black BN

    E 151

    		 Enterovirus Infection
    Brilliant black BN (E151) is an azo dye and a food colorant . Brilliant black BN is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. Brilliant black BN has the potential for the investigation of contagious disease .
    Brilliant Black BN
  • HY-N2562
    Norwogonin

    5,7,8-Trihydroxyflavone

    		 Enterovirus Infection
    Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC50 of 31.83 μg/ml
    Norwogonin
  • HY-157082
    ZHSI-1

    		Enterovirus Infection
    ZHSI-1 is an EV71 (Enterovirus 71) inhibitor that inhibits EV71/CVA16 replication and virus-induced pyroptosis associated with viral pathogenesis. ZHSI-1 effectively prevents EV71 infection in neonatal and young mice in animal models. ZHSI-1 can be used to study viral infections such as hand, foot and mouth disease (HFMD) .
    ZHSI-1
  • HY-125713
    Ganoderic acid Y

    		Glucosidase Enterovirus Infection
    Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating .
    Ganoderic acid Y
  • HY-145932
    DMA-135 hydrochloride

    		Enterovirus Infection
    DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. DMA-135 hydrochloride binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM). DMA-135 hydrochloride has no significant toxicity in cell-based studies . DMA-135 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    DMA-135 hydrochloride
  • HY-106254
    Vapendavir

    BTA798

    		 Enterovirus Infection
    Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains .
    Vapendavir
  • HY-147700
    Antiviral agent 21

    		Enterovirus Infection
    Antiviral agent 21 (Compound 4) is an anti-EV71 agent .
    Antiviral agent 21
  • HY-106254A
    Vapendavir diphosphate
    2 Publications Verification

    BTA798 diphosphate

    		 Enterovirus Infection Inflammation/Immunology
    Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains .
    Vapendavir diphosphate
  • HY-16561A
    cis-Resveratrol

    		Enterovirus Infection
    cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC50s of 12.2 µM and 37.6 µM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively .
    cis-Resveratrol
  • HY-151924
    Antiviral agent 23

    		Enterovirus Infection
    Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection .
    Antiviral agent 23
  • HY-N0306
    Hederasaponin B

    		Enterovirus Infection
    Hederasaponin B, isolated from Hedera helix, has broad-spectrum antiviral activity against various subgenotypes of Enterovirus 71 (EV71).
    Hederasaponin B
  • HY-N0923
    Corydaline

    (+)-Corydaline; Corydalin

    		 Cholinesterase (ChE) Enterovirus Opioid Receptor Neurological Disease
    Corydaline ((+)-Corydaline), an isoquinoline alkaloid isolated from Corydalis yanhusuo, is an AChE inhibitor with an IC50 of 226 µM. Corydaline is a μ-opioid receptor (Ki of 1.23 µM) agonist and inhibits enterovirus 71 (EV71) replication (IC50 of 25.23 µM). Corydaline has anti-angiogenic, anti-allergic and gastric-emptying and antinociceptive activities .
    Corydaline
  • HY-151926
    Antiviral agent 24

    		Enterovirus Infection
    Antiviral agent 24 is a potent antiviral agent with EC50 values of 0.101, 19.9, 91.2 µM for EV71, CVA21, EV68, respectively. Antiviral agent 24 inhibits METTL3/METTL14 activity in a dose-dependent manner .
    Antiviral agent 24
  • HY-N2036
    Mosloflavone

    		Enterovirus Bacterial Infection
    Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with  anti-EV71 activity. Mosloflavone  inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation.
    Mosloflavone
  • HY-W127716
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2

    		Fluorescent Dye Cancer
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
  • HY-22055B
    AN-12-H5 intermediate-1

    (2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate

    		 Others Infection
    AN-12-H5 intermediate-1 ((2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate) is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
    AN-12-H5 intermediate-1
  • HY-W047496
    AN-12-H5 intermediate-2

    		Others Infection
    AN-12-H5 intermediate-2 is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
    AN-12-H5 intermediate-2
  • HY-W451820
    AN-12-H5 intermediate-3

    		Others Infection
    AN-12-H5 intermediate-3 is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
    AN-12-H5 intermediate-3
  • HY-145850
    EV-A71-IN-1

    		Enterovirus Infection
    EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM) .
    EV-A<em>71</em>-IN-1
  • HY-N6025
    Clemastanin B

    		Influenza Virus Infection Inflammation/Immunology
    Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities .
    Clemastanin B

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