2. Anti-infection
  3. Enterovirus
  4. Vapendavir diphosphate

Vapendavir diphosphate  (Synonyms: BTA798 diphosphate)

Cat. No.: HY-106254A Purity: 98.75%
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Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains.

For research use only. We do not sell to patients.

Vapendavir diphosphate Chemical Structure

Vapendavir diphosphate Chemical Structure

CAS No. : 1198151-75-5

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Solid + Solvent
10 mM * 1 mL in DMSO
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10 mM * 1 mL in DMSO USD 267 In-stock
Solid
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Based on 2 publication(s) in Google Scholar

Other Forms of Vapendavir diphosphate:

Vapendavir diphosphate Related Antibodies

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Description

Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].

IC50 & Target

EC50: 0.5-1.4 μM (EV71 strains)[1][2].
In Vitro

Vapendavir (BTA798) efficiently inhibit the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Vapendavir diphosphate Related Antibodies
Clinical Trial
Molecular Weight

578.45

Formula

C21H32N4O11P2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C12.OP(O)(O)=O.OP(O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 6.75 mg/mL (11.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7288 mL 8.6438 mL 17.2876 mL
5 mM 0.3458 mL 1.7288 mL 3.4575 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7288 mL 8.6438 mL 17.2876 mL 43.2189 mL
5 mM 0.3458 mL 1.7288 mL 3.4575 mL 8.6438 mL
10 mM 0.1729 mL 0.8644 mL 1.7288 mL 4.3219 mL
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Vapendavir diphosphate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vapendavir diphosphate1198151-75-5BTA798 diphosphateEnterovirusRhinovirusHRVHRVsHEVHEVsInhibitorinhibitorinhibit

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