1198151-75-5
1198151-75-5
Chemical Structure
Vapendavir diphosphate
Synonym(s): BTA798 diphosphate
- CAS No.: 1198151-75-5
- Formula:C21H32N4O11P2
- Molecular Weight:578.45
IUPAC Name: 3-ethoxy-6-(2-(1-(6-methylpyridazin-3-yl)piperidin-4-yl)ethoxy)benzo[d]isoxazole bis(phosphate)
InChIKey: MIUFDXZDQWMWRR-UHFFFAOYSA-N
SMILES: CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C12.OP(O)(O)=O.OP(O)(O)=O
Biological Activity: Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Vapendavir diphosphate | 98.72% | Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains. | ||||||||||||||||||||
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Vapendavir diphosphate (Standard) | ≥98% | Vapendavir diphosphate (Standard) is the analytical standard of Vapendavir diphosphate (HY-106254A). This product is intended for research and analytical applications. Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains. | ||||||||||||||||||||
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References
- [1]. Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2. [Content Brief]
- [2]. Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5. [Content Brief]
