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Cat. No.: HY-W741575

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Iloperidone carboxylic acid

(Synonyms: P95-12113)

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Based on 1 Customer Validation

Iloperidone carboxylic acid (P95-12113) is the metabolite of Iloperidone (HY-17410). Iloperidone carboxylic acid exhibits good affinity for 5-HT2A receptor with pK_i of 8.15, and moderate affinity for adrenergic receptor α1/α2B/α2C.

For research use only. We do not sell to patients.

Purity: 98.0%
CAS No.: 475110-48-6
Formula: C₂₃H₂₅FN₂O₅
Molecular Weight:428.45

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Iloperidone carboxylic acid Chemical Structure

CAS No.: 475110-48-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

Human 5-HT_2A Receptor

8.15 (pKi)

5-HT_2A Receptor

rat α1-adrenergic receptor

7.67 (pKi)

human α2C-adrenoceptor

7.32 (pKi)

human α2B-adrenoceptor

7.08 (pKi)

human α2A-adrenoceptor

6.42 (pKi)

Rat D₃ Receptor

6.11 (pKi)

Human D₁ Receptor

5.94 (pKi)

Human 5-HT₆ Receptor

5.59 (pKi)

All 5-HT Receptor Isoforms :

All Adrenergic Receptor Isoforms :

All Dopamine Receptor Isoforms :

Chemical Information

CAS No. 475110-48-6
Appearance Solid
Molecular Weight 428.45
Formula C₂₃H₂₅FN₂O₅
Color White to off-white
SMILES

COC1=C(OCCCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)C=CC(C(O)=O)=C1
Synonyms

P95-12113
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Subramanian N, et al., Receptor profile of P88-8991 and P95-12113, metabolites of the novel antipsychotic iloperidone. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Apr;26(3):553-60. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Iloperidone carboxylic acid

High-Throughput Bioactive Compound Library

All 5-HT Receptor Isoforms

All Adrenergic Receptor Isoforms

All Dopamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Iloperidone carboxylic acid Related Classifications

HY-W741575 Related Classifications