EV-A71-IN-1
EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM).
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- No. CAS: 2413648-96-9
- Fòrmula: C21H15N5S
- Peso molecular:369.44
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Descripciòn
In Vitro
EV-A71-IN-1 (compound 12s) shows activity not only against different EV-A71 strains (BrCr, GZ-CII, EV71/HeN09 and EV71/G082) but also against other representative enteroviruses (CV-A16, EV-D68, Echov-6, CV-B2 and CV-B6)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2413648-96-9
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Peso molecular 369.44
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Fòrmula C21H15N5S
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SMILES
C1(C2=CC=C(C=C2)NC3=NC(C4=CN=C5N=CC=CN45)=CS3)=CC=CC=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EV-A71-IN-1 Related Classifications
HY-145850 Related Classifications
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