2413648-96-9
Chemical Structure
EV-A71-IN-1
- CAS No.: 2413648-96-9
- Formula:C21H15N5S
- Molecular Weight:369.44
IUPAC Name: N-([1,1'-biphenyl]-4-yl)-4-(imidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine
InChIKey: RLAGELDZWDHQJS-UHFFFAOYSA-N
SMILES: C1(C2=CC=C(C=C2)NC3=NC(C4=CN=C5N=CC=CN45)=CS3)=CC=CC=C1
Biological Activity: EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM)[1].
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EV-A71-IN-1 | EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM). | |||||||||||||||||||||
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Keywords
