1. Cell Cycle/DNA Damage Epigenetics
  2. Aurora Kinase
  3. Aurora kinase inhibitor-9

Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity.

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Aurora kinase inhibitor-9

Aurora kinase inhibitor-9 화학구조

CAS No. : 2419107-09-6

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제품 설명

Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity[1].

IC50 & Target[1]

Aurora A

0.093 μM (IC50)

Aurora B

0.09 μM (IC50)

분자량

454.33

화학식

C19H17Cl2N3O4S

CAS No.
SMILES

CCOC(C1=C(C2=C(C=C(C=C2N=C1)Cl)Cl)NC3=CC(S(=O)(NC)=O)=CC=C3)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Aurora kinase inhibitor-9
Cat. No.:
HY-147703
수량:
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