1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. Aurora Kinase
  4. Aurora B Inhibitors

Aurora B Inhibitors

Aurora A

Aurora B

Aurora C

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Sorry. There is currently no product that acts on isoform Aurora B together.

Please try each isoform separately.

Aurora B Specific Inhibitors
Product Name Aurora B Aurora A Aurora C Aurora B Selectivity Purity
Barasertib-HQPA
Aurora B, IC50: 0.37 nM
    Selective Inhibitor 99.64%
Hesperadin
Aurora B, IC50: 250 nM
    Selective Inhibitor 98.48%
CYC-116
Aurora B, Ki: 9.2 nM
Aurora A, Ki: 8 nM
  Selective Inhibitor 98.17%
Aurora B inhibitor 1
Aurora B, Ki: 0.01 μM
    Selective Inhibitor
Alisertib
Aurora B, IC50: 396.5 nM
Aurora A, IC50: 1.2 nM
  Pan Inhibitor 99.84%
AT9283
Aurora B, IC50: 3 nM
Aurora A, IC50: 3 nM
  Pan Inhibitor 99.13%
Tozasertib
Aurora B, Ki: 18 nM
Aurora A, Ki: 0.6 nM
Aurora C, Ki: 4.6 nM
Pan Inhibitor 99.85%
Aurora inhibitor 1
Aurora B, IC50: 13 nM
Aurora A, IC50: 4 nM
  Pan Inhibitor
NU6140
Aurora B, IC50: 35 nM
Aurora A, IC50: 67 nM
  Pan Inhibitor >99.0%
GSK-1070916
Aurora B, Ki: 0.38 nM
 
Aurora C, Ki: 1.5 nM
Pan Inhibitor 99.55%
Danusertib
Aurora B, IC50: 79 nM
Aurora A, IC50: 13 nM
Aurora C, IC50: 61 nM
Pan Inhibitor 99.44%
JNJ-7706621
Aurora B, IC50: 15 nM
Aurora A, IC50: 11 nM
  Pan Inhibitor 99.91%
PF-03814735
Aurora 2, IC50: 5 nM
Aurora 1, IC50: 0.8 nM
  Pan Inhibitor 99.77%
Reversine
Aurora B, IC50: 500 nM
Aurora A, IC50: 400 nM
Aurora C, IC50: 400 nM
Pan Inhibitor 99.25%
TAK-901
Aurora B, IC50: 15 nM
Aurora A, IC50: 21 nM
  Pan Inhibitor 99.80%
SNS-314
Aurora B, IC50: 31 nM
Aurora A, IC50: 9 nM
Aurora C, IC50: 6 nM
Pan Inhibitor 99.81%
ZM-447439
Aurora B, IC50: 130 nM
Aurora A, IC50: 110 nM
  Pan Inhibitor 98.59%
Aurora A inhibitor I
Aurora B, IC50: 3.4 μM
Aurora A, IC50: 3.4 nM
  Pan Inhibitor 98.74%
PHA-680632
Aurora B, IC50: 135 nM
Aurora A, IC50: 27 nM
Aurora C, IC50: 120 nM
Pan Inhibitor 98.02%
CCT129202
Aurora B, IC50: 198 nM
Aurora A, IC50: 42 nM
Aurora C, IC50: 227 nM
Pan Inhibitor >95.0%
CCT 137690
Aurora B, IC50: 25 nM
Aurora A, IC50: 15 nM
Aurora C, IC50: 19 nM
Pan Inhibitor 98.33%
SCH-1473759 hydrochloride
Aurora B, IC50: 13 nM
Aurora A, IC50: 4 nM
  Pan Inhibitor 99.67%
Ilorasertib
Aurora B, IC50: 7 nM
Aurora B (Y156H), IC50: 12 nM
Aurora A, IC50: 120 nM
Aurora C, IC50: 1 nM
Pan Inhibitor
SCH-1473759
Aurora B, IC50: 13 nM
Aurora A, IC50: 4 nM
  Pan Inhibitor 98.20%
Cenisertib
Aurora-B
Aurora-A
  Pan Inhibitor