942487-16-3

PF-03814735 Chemical Structure
942487-16-3

Chemical Structure

PF-03814735

  • CAS No.: 942487-16-3
  • Formula:C23H25F3N6O2
  • Molecular Weight:474.48

IUPAC Name: N-(2-((1S,4R)-6-((4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl)-2-oxoethyl)acetamide

InChIKey: RYYNGWLOYLRZLK-RBUKOAKNSA-N

SMILES: O=C(CNC(C)=O)N1[C@@H]2C3=C(C=C(NC4=NC(NC5CCC5)=C(C(F)(F)F)C=N4)C=C3)[C@H]1CC2

Biological Activity: PF-03814735 is a potent, orally available, ATP-competitive and reversible aurora A and aurora B inhibitor with IC50s of 0.8 and 0.5 nM, respectively.

Cat. No. Nom du produit Pureté Description Pricing
HY-14574 		PF-03814735 99.45% PF-03814735 is a potent, orally available, ATP-competitive and reversible aurora A and aurora B inhibitor with IC50s of 0.8 and 0.5 nM, respectively.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

Keywords