942487-16-3
942487-16-3
Chemical Structure
PF-03814735
- CAS No.: 942487-16-3
- Formula:C23H25F3N6O2
- Molecular Weight:474.48
IUPAC Name: N-(2-((1S,4R)-6-((4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl)-2-oxoethyl)acetamide
InChIKey: RYYNGWLOYLRZLK-RBUKOAKNSA-N
SMILES: O=C(CNC(C)=O)N1[C@@H]2C3=C(C=C(NC4=NC(NC5CCC5)=C(C(F)(F)F)C=N4)C=C3)[C@H]1CC2
Biological Activity: PF-03814735 is a potent, orally available, ATP-competitive and reversible aurora A and aurora B inhibitor with IC50s of 0.8 and 0.5 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-03814735 | 99.45% | PF-03814735 is a potent, orally available, ATP-competitive and reversible aurora A and aurora B inhibitor with IC50s of 0.8 and 0.5 nM, respectively. | ||||||||||||||||||||
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Keywords
