722543-31-9
Chemical Structure
Barasertib
Synonym(s): AZD1152
- CAS No.: 722543-31-9
- Formula:C26H31FN7O6P
- Molecular Weight:587.54
IUPAC Name: 2-(ethyl(3-((4-((5-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyl dihydrogen phosphate
InChIKey: GBJVVSCPOBPEIT-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(F)=C1)CC2=CC(NC3=C4C=CC(OCCCN(CC)CCOP(O)(O)=O)=CC4=NC=N3)=NN2
Biological Activity: Barasertib (AZD1152), a pro-drug of Barasertib-hQPA, is a highly selective Aurora B inhibitor with an IC50 of 0.37 nM in a cell-free assay. Barasertib (AZD1152) induces growth arrest and apoptosis in cancer cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Barasertib | 99.50% | Barasertib (AZD1152), a pro-drug of Barasertib-hQPA, is a highly selective Aurora B inhibitor with an IC50 of 0.37 nM in a cell-free assay. Barasertib (AZD1152) induces growth arrest and apoptosis in cancer cells. | ||||||||||||||||||||
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Barasertib (Standard) | ≥98% | Barasertib (Standard) is the analytical standard of Barasertib. This product is intended for research and analytical applications. Barasertib (AZD1152), a pro-drug of Barasertib-hQPA, is a highly selective Aurora B inhibitor with an IC50 of 0.37 nM in a cell-free assay. Barasertib (AZD1152) induces growth arrest and apoptosis in cancer cells. | ||||||||||||||||||||
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Similarity Score 0.90
HY-10127ABarasertib dihydrochloride -
Similarity Score 0.81
HY-10126Barasertib-HQPA -
Similarity Score 0.81
HY-175526Aurora kinase ligand-1 -
Similarity Score 0.50
HY-147994EGFR/HER2-IN-5 -
Similarity Score 0.50
HY-168581c-Kit-IN-8 -
Similarity Score 0.50
HY-112802Ubavitinib -
Similarity Score 0.49
HY-184329PROTAC AURKB Degrader-1 -
Similarity Score 0.49
HY-15467AZM323881 hydrochloride -
Similarity Score 0.49
HY-177989ER121 -
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