945595-80-2
945595-80-2
Chemical Structure
AMG 900
- CAS No.: 945595-80-2
- Formula:C28H21N7OS
- Molecular Weight:503.58
IUPAC Name: N-(4-((3-(2-aminopyrimidin-4-yl)pyridin-2-yl)oxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine
InChIKey: IVUGFMLRJOCGAS-UHFFFAOYSA-N
SMILES: CC1=CSC(C2=NN=C(C3=C2C=CC=C3)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=CC=NC(N)=N6)=C1
Biological Activity: AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor with IC50 of 5 nM, 4 nM and 1 nM for Aurora A, B and C, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
AMG 900 | 98.82% | AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor with IC50 of 5 nM, 4 nM and 1 nM for Aurora A, B and C, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.51
HY-14177Raf inhibitor 1 -
Similarity Score 0.51
HY-110101ARN272 -
Similarity Score 0.50
HY-145419IRE1α kinase-IN-4 -
Similarity Score 0.50
HY-14177ARaf inhibitor 1 dihydrochloride -
Similarity Score 0.50
HY-145420IRE1α kinase-IN-5 -
Similarity Score 0.50
HY-168767CA IX-IN-3 -
Similarity Score 0.49
HY-111940Omzirafenib -
Similarity Score 0.49
HY-145418IRE1α kinase-IN-3 -
Similarity Score 0.49
HY-13023AMG-Tie2-1 -
Explore the MedChemAI to find more analogs
