1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. Aurora Kinase
  4. Aurora A Inhibitors

Aurora A Inhibitors

Aurora A

Aurora B

Aurora C

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Sorry. There is currently no product that acts on isoform Aurora A together.

Please try each isoform separately.

Aurora A Specific Inhibitors
Product Name Aurora A Aurora B Aurora C Aurora A Selectivity Purity
Alisertib
Aurora A, IC50: 1.2 nM
Aurora B, IC50: 396.5 nM
  Selective Inhibitor ≥95.0%
MK-5108
Aurora A, IC50: 64 pM
    Selective Inhibitor ≥98.0%
TAS-119
Aurora A, IC50: 1 nM
Aurora B, IC50: 95 nM
  Selective Inhibitor 98.27%
CD532
Aurora A, IC50: 45 nM
    Selective Inhibitor
LY3295668
Aurora A, IC50: 0.8 nM
    Selective Inhibitor 99.61%
KW-2449
Aurora A, IC50: 48 nM
    Selective Inhibitor 99.85%
MLN8054
Aurora A, IC50: 4 nM
    Selective Inhibitor ≥98.0%
ENMD-2076
Aurora A, IC50: 14 nM
    Selective Inhibitor 99.12%
CYC-116
Aurora A, Ki: 8 nM
Aurora B, Ki: 9.2 nM
  Selective Inhibitor ≥98.0%
MK-8745
Aurora A, IC50: 0.6 nM
    Selective Inhibitor 99.28%
TCS7010
Aurora A, IC50: 3.4 nM
Aurora B, IC50: 3.4 μM
  Selective Inhibitor 99.22%
Aurora kinase inhibitor-3
Aurora A, IC50: 42 nM
    Selective Inhibitor 98.98%
JB170
Aurora A, DC50: 28 nM
Aurora A, Kd: 99 nM
Aurora A, EC50: 193 nM
    Selective Inhibitor
AKI603
Aurora A, IC50: 12.3 nM
    Selective Inhibitor 98.05%
Tozasertib
Aurora A, Ki: 0.6 nM
Aurora B, Ki: 18 nM
Aurora C, Ki: 4.6 nM
Pan Inhibitor 99.94%
AT9283
Aurora A, IC50: 3 nM
Aurora B, IC50: 3 nM
  Pan Inhibitor 99.61%
Danusertib
Aurora A, IC50: 13 nM
Aurora B, IC50: 79 nM
Aurora C, IC50: 61 nM
Pan Inhibitor ≥98.0%
JNJ-7706621
Aurora A, IC50: 11 nM
Aurora B, IC50: 15 nM
  Pan Inhibitor 99.96%
PF-03814735
Aurora 1, IC50: 0.8 nM
Aurora 2, IC50: 5 nM
  Pan Inhibitor 99.82%
Reversine
Aurora A, IC50: 400 nM
Aurora B, IC50: 500 nM
Aurora C, IC50: 400 nM
Pan Inhibitor 99.40%
SNS-314 mesylate
Aurora A, IC50: 9 nM
Aurora B, IC50: 31 nM
Aurora C, IC50: 6 nM
Pan Inhibitor 99.90%
ZM-447439
Aurora A, IC50: 110 nM
Aurora B, IC50: 130 nM
  Pan Inhibitor 99.19%
Cenisertib
Aurora-A
Aurora-B
  Pan Inhibitor 99.56%
XL228
Aurora A, IC50: 3.1 nM
    Pan Inhibitor 99.61%
PHA-680632
Aurora A, IC50: 27 nM
Aurora B, IC50: 135 nM
Aurora C, IC50: 120 nM
Pan Inhibitor 98.48%
Ilorasertib hydrochloride
Aurora A, IC50: 120 nM
Aurora B, IC50: 7 nM
Aurora B (Y156H), IC50: 12 nM
Aurora C, IC50: 1 nM
Pan Inhibitor 98.91%
PF 477736
Aurora-A, IC50: 23 nM
    Pan Inhibitor 99.21%
TAK-901
Aurora A, IC50: 21 nM
Aurora B, IC50: 15 nM
  Pan Inhibitor ≥98.0%
SCH-1473759 hydrochloride
Aurora A, IC50: 4 nM
Aurora B, IC50: 13 nM
  Pan Inhibitor 99.79%
CCT 137690
Aurora A, IC50: 15 nM
Aurora B, IC50: 25 nM
Aurora C, IC50: 19 nM
Pan Inhibitor 99.10%
CCT129202
Aurora A, IC50: 42 nM
Aurora B, IC50: 198 nM
Aurora C, IC50: 227 nM
Pan Inhibitor 98.24%
ENMD-2076 Tartrate
Aurora A, IC50: 1.86 nM
    Pan Inhibitor 98.87%
NU6140
Aurora A, IC50: 67 nM
Aurora B, IC50: 35 nM
  Pan Inhibitor ≥99.0%
SP-96
Aurora A, IC50: 18.975 nM
Aurora B, IC50: 0.316 nM
  Pan Inhibitor 98.03%
Ilorasertib
Aurora A, IC50: 120 nM
Aurora B, IC50: 7 nM
Aurora B (Y156H), IC50: 12 nM
Aurora C, IC50: 1 nM
Pan Inhibitor ≥98.0%
SCH-1473759
Aurora A, IC50: 4 nM
Aurora B, IC50: 13 nM
  Pan Inhibitor 98.20%
Aurora inhibitor 1
Aurora A, IC50: 4 nM
Aurora B, IC50: 13 nM
  Pan Inhibitor
Glycyl H-1152 hydrochloride
Aurora A, IC50: 2.35 μM
    Pan Inhibitor
Aurora kinase inhibitor-2
Aurora A, IC50: 310 nM
Aurora B, IC50: 240 nM
  Pan Inhibitor 99.19%
GW779439X
Aurora A
    Inhibitor