1000669-72-6
1000669-72-6
Chemical Structure
KW-2449
- CAS No.: 1000669-72-6
- Formula:C20H20N4O
- Molecular Weight:332.40
IUPAC Name: (E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone
InChIKey: YYLKKYCXAOBSRM-JXMROGBWSA-N
SMILES: O=C(C1=CC=C(/C=C/C2=NNC3=C2C=CC=C3)C=C1)N4CCNCC4
Biological Activity: KW-2449 is a multi-targeted kinase inhibitor of FLT3, ABL, ABLT315I and Aurora kinase with IC50s of 6.6, 14, 4 and 48 nM, respectively.
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KW-2449 | 99.91% | KW-2449 is a multi-targeted kinase inhibitor of FLT3, ABL, ABLT315I and Aurora kinase with IC50s of 6.6, 14, 4 and 48 nM, respectively. | ||||||||||||||||||||
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KW-2449 (Standard) | ≥98% | KW-2449 (Standard) is the analytical standard of KW-2449 (HY-10339). This product is intended for research and analytical applications. KW-2449 is a multi-targeted kinase inhibitor of FLT3, ABL, ABLT315I and Aurora kinase with IC50s of 6.6, 14, 4 and 48 nM, respectively. | ||||||||||||||||||||
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Keywords
