1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. Aurora Kinase
  4. Aurora Kinase Isoform

Aurora Kinase

 

Aurora Kinase Related Products (14):

Cat. No. Product Name Effect Purity
  • HY-15767
    TAK-632
    Inhibitor 98.46%
    TAK-632 is a potent pan-RAF inhibitor with IC50 of 1.4, 2.4 and 8.3 nM for CRAF, BRAFV600E, BRAFWT, respectively.
  • HY-112273A
    CD532 hydrochloride
    Inhibitor 99.31%
    CD532 hydrochloride is a potent Aurora A kinase inhibitor with an IC50 of 45 nM.
  • HY-18161
    CCT241736
    Inhibitor 98.09%
    CCT241736 is a potent and orally bioavailable dual FLT3 and Aurora kinase inhibitor, which inhibits Aurora kinases (Aurora-A Kd, 7.5 nM, IC50, 38 nM; Aurora-B Kd, 48 nM), FLT3 kinase (Kd, 6.2 nM), and FLT3 mutants including FLT3-ITD (Kd, 38 nM) and FLT3(D835Y) (Kd, 14 nM).
  • HY-145601
    Tinengotinib
    Modulator
    Tinengotinib is the modulator of one or more protein kinases such as Aurora kinase and VEGFR kinase.
  • HY-126249
    AAPK-25
    Inhibitor 98.31%
    AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3Ser10 phosphorylation and followed by a surge in apoptosis.
  • HY-148063
    DB0614
    DB0614 (Example 21) is a bifunctional compound targeted protein degradation of kinases.
  • HY-N3737
    Derrone
    Inhibitor
    Derrone, a prenylated isoflavones, is an Aurora kinase inhibitor, with IC50 values of 6 and 22.3 μM against Aurora B and Aurora A, respectively.
  • HY-115932
    Aurora kinase-IN-1
    Inhibitor
    Aurora kinase-IN-1 (Compound 9) is a potent inhibitor of aurora kinase.
  • HY-113894
    Retreversine
    Retreversine is an inactive control for Reversine.
  • HY-144991
    Aurora kinase inhibitor-8
    Inhibitor 98.10%
    Aurora kinase inhibitor-8 is a highly selective inhibitor of the Aurora kinases.
  • HY-124330
    Tripolin A
    Inhibitor
    Tripolin A ((E)-Tripolin A) is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and 7 μM for Aurora A and Aurora B, respectively.
  • HY-144438
    Aurora/LIM kinase-IN-1
    Inhibitor
    Aurora/LIM kinase-IN-1 (Compound F114) is a potent and dual inhibitor of aurora and lim kinase.
  • HY-143713
    Aurora A inhibitor 1
    Inhibitor
    Aurora A inhibitor 1 is a potent and selective inhibitor of Aurora A.
  • HY-12201S
    TAK-901-d3
    Inhibitor