VEGFR-2/AURKA-IN-1
VEGFR-2/AURKA-IN-1 (compound 5e) is a thiazolidin-4-one derivative with antiglioma activity (IC50: 6.43 μM, LN229). VEGFR-2/AURKA-IN-1 has affinity for AURKA and VEGFR-2 and is a potential ligand. VEGFR-2/AURKA-IN-1 causes DNA strand breaks and exhibits cytotoxic and anticancer potential.
For research use only. We do not sell to patients.
- Formula: C20H15ClF6N2O4S
- Molecular Weight:528.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
AURKA, VEGFR-2[1]
Chemical Information
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Molecular Weight 528.85
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Formula C20H15ClF6N2O4S
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SMILES
FC(F)(F)COC1=C(C(NN2C(C3=CC=C(Cl)C=C3)SCC2=O)=O)C=C(OCC(F)(F)F)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)