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Cat. No.: HY-149693

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Aurora kinase inhibitor-11

Aurora kinase inhibitor-11 (compound 25) is an inhibitor of Aurora Kinase with an IC₅₀ of 0.14 μM. Aurora kinase inhibitor-11 has anticancer activity.

For research use only. We do not sell to patients.

CAS No.: 923946-98-9
Formula: C₁₁H₁₀BrN₃OS
Molecular Weight:312.19

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Aurora kinase inhibitor-11 Chemical Structure

CAS No.: 923946-98-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Aurora kinase inhibitor-11 (compound 25) is an inhibitor of Aurora Kinase with an IC₅₀ of 0.14 μM. Aurora kinase inhibitor-11 has anticancer activity^[1].

All Aurora Kinase Isoforms :

Chemical Information

CAS No. 923946-98-9
Molecular Weight 312.19
Formula C₁₁H₁₀BrN₃OS
SMILES

CNC(C1=CC=C(C=C1)NC2=NC=C(S2)Br)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Andersen C B et al. Discovery of selective aminothiazole aurora kinase inhibitors[J]. ACS chemical biology, 2008, 3(3): 180-192.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
Purity & Documentation
References

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Aurora kinase inhibitor-11

All Aurora Kinase Isoforms