Benzyl nicotinate

Name: Benzyl nicotinate
Brand: MedChemExpress
SKU: HY-B1555
Rating: 4.5 (0 reviews)

製品番号: HY-B1555 純度: 97.29%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

Benzyl nicotinate is a vasodilator that increases skin oxygenation levels by increasing skin blood flow.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Benzyl nicotinate 構造式

CAS 番号 : 94-44-0

容量	価格（税別）	在庫状況	数量
Solid or liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 27	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 27	在庫あり	Estimated Time of Arrival: December 31
Solid or liquid
1 g	$25	在庫あり	Estimated Time of Arrival: December 31
5 g	$50	在庫あり	Estimated Time of Arrival: December 31
10 g		お問い合わせ
50 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of Benzyl nicotinate:

Benzyl nicotinate (Standard) お問い合わせ

おすすめ

•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Benzyl nicotinate is a vasodilator that increases skin oxygenation levels by increasing skin blood flow^[1]^[2].

体外実験

Benzyl nicotinate crosses the skin, releases nicotinic acid by enzymatic hydrolysis, increases local cutaneous blood flow, and promotes skin oxygenation. Benzyl nicotinate can be used for for particulate encapsulation, skin penetration and detection for its lipophilicity^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Benzyl nicotinate (2.5% w/w, topical administration to the skin, single dose) affects the lipid structure, increases the lipid fluidity in the stratum corneum, exhibits good skin oxygenation levels in BALB/c mouse models^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	BALB/c mouse models^[3]
Dosage:	2.5% w/w
Administration:	topical administration to the skin, single dose
Result:	Increased the lipid fluidity in the stratum corneum.

分子量

213.24

分子式

C₁₃H₁₁NO₂

CAS 番号

94-44-0

Appearance

<24°C Solid,>24°C Liquid

Color

Off-white to light yellow

SMILES

O=C(C1=CC=CN=C1)OCC2=CC=CC=C2

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Store at room temperature 3 years

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature 3 years)

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (468.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.6896 mL	23.4478 mL	46.8955 mL
5 mM	0.9379 mL	4.6896 mL	9.3791 mL
10 mM	0.4690 mL	2.3448 mL	4.6896 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.60%

Select Batch:

データシート (271 KB) SDS (393 KB)

COA (246 KB) HNMR (117 KB) RP-HPLC (341 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Erjavec V, et al. In vivo study of liposomes as drug carriers to oral mucosa using EPR oximetry. Int J Pharm. 2006;307(1):1-8. [Content Brief]

[2]. Petelin M, et al. In vivo study of different ointments for drug delivery into oral mucosa by EPR oximetry. Int J Pharm. 2004;270(1-2):83-91. [Content Brief]

[3]. Abramović Z, et al., Influence of nanosized delivery systems with benzyl nicotinate and penetration enhancers on skin oxygenation. Int J Pharm. 2008 Jul 9;359(1-2):220-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.6896 mL	23.4478 mL	46.8955 mL	117.2388 mL
	5 mM	0.9379 mL	4.6896 mL	9.3791 mL	23.4478 mL
	10 mM	0.4690 mL	2.3448 mL	4.6896 mL	11.7239 mL
	15 mM	0.3126 mL	1.5632 mL	3.1264 mL	7.8159 mL
	20 mM	0.2345 mL	1.1724 mL	2.3448 mL	5.8619 mL
	25 mM	0.1876 mL	0.9379 mL	1.8758 mL	4.6896 mL
	30 mM	0.1563 mL	0.7816 mL	1.5632 mL	3.9080 mL
	40 mM	0.1172 mL	0.5862 mL	1.1724 mL	2.9310 mL
	50 mM	0.0938 mL	0.4690 mL	0.9379 mL	2.3448 mL
	60 mM	0.0782 mL	0.3908 mL	0.7816 mL	1.9540 mL
	80 mM	0.0586 mL	0.2931 mL	0.5862 mL	1.4655 mL
	100 mM	0.0469 mL	0.2345 mL	0.4690 mL	1.1724 mL