2. Neuronal Signaling NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Amyloid-β Reactive Oxygen Species (ROS)
  4. Biotinoyl tripeptide-1

Biotinoyl tripeptide-1  (Synonyms: Biotinyl-GHK; Bio-GHK)

Art. -Nr.: HY-125616 Reinheit: 99.02%
COA
SDS
Handling Instructions Technical Support

Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Kundenspezifische Peptidsynthese

Biotinoyl tripeptide-1

Biotinoyl tripeptide-1 Chemische Struktur

CAS. Nr. : 299157-54-3

Größe Preis Verfügbarkeit Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
Solid
25 mg Auf Lager
50 mg Auf Lager
100 mg Auf Lager
250 mg Auf Lager
500 mg   Angebot einholen  
1 g   Angebot einholen  

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

This product is a controlled substance and not for sale in your territory.

Kundenbewertung

Based on 1 Customer Validation

Biotinoyl tripeptide-1 Related Antibodies

Top Publications Citing Use of Products

  • Biologische Aktivität

  • Reinheit & Dokumentation

  • Verweise

  • Kundenbewertung

Beschreibung

Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases[1][2].

In Vitro

Biotinoyl tripeptide-1 (2 mM) can inhibit the binding of HABA to streptavidin (IC50: 30 µM), indicating that it has a higher affinity for streptavidin[2].
Biotinoyl tripeptide-1 (0-30 μM, 45 min) dose-dependently alters the oxidative activity of ascorbic acid (ASC) induced by Cu-Aβ complexes by coordinating with copper ions and reducing the generation of ROS[2].
Biotinoyl tripeptide-1 (0-120 μM, 100 min) effectively inhibits the production of carbonylated amyloid β in acrolein-induced Aβ1-16[2].
Biotinoyl tripeptide-1 (20 μM, 50 h) inhibits the amyloid aggregation of Aβ in Aβ42[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Biotinoyl tripeptide-1 Related Antibodies
Molekulargewicht

566.67

Formel

C24H38N8O6S
CAS. Nr.
Appearance

Solid

Color

White to off-white

Sequence

{Biotinyl}-Gly-His-Lys
Sequence Shortening

{Biotinyl}-GHK
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 87.5 mg/mL (154.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7647 mL 8.8235 mL 17.6470 mL
5 mM 0.3529 mL 1.7647 mL 3.5294 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7647 mL 8.8235 mL 17.6470 mL 44.1174 mL
5 mM 0.3529 mL 1.7647 mL 3.5294 mL 8.8235 mL
10 mM 0.1765 mL 0.8823 mL 1.7647 mL 4.4117 mL
15 mM 0.1176 mL 0.5882 mL 1.1765 mL 2.9412 mL
20 mM 0.0882 mL 0.4412 mL 0.8823 mL 2.2059 mL
25 mM 0.0706 mL 0.3529 mL 0.7059 mL 1.7647 mL
30 mM 0.0588 mL 0.2941 mL 0.5882 mL 1.4706 mL
40 mM 0.0441 mL 0.2206 mL 0.4412 mL 1.1029 mL
50 mM 0.0353 mL 0.1765 mL 0.3529 mL 0.8823 mL
60 mM 0.0294 mL 0.1471 mL 0.2941 mL 0.7353 mL
80 mM 0.0221 mL 0.1103 mL 0.2206 mL 0.5515 mL
100 mM 0.0176 mL 0.0882 mL 0.1765 mL 0.4412 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Biotinoyl tripeptide-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Biotinoyl tripeptide-1299157-54-3Biotinyl-GHK Bio-GHKBiotinoyl tripeptide1Biotinoyl tripeptide 1Amyloid-βReactive Oxygen Species (ROS)β-amyloid peptideAβAbetaBiopeptidesAlzheimer's diseaseantioxidantspeptidesInhibitorinhibitorinhibit

Ihre kürzlich angesehenen Produkte:

Online-Anfrage

Your information is safe with us. * Required Fields.

Produktname

  

Requested Quantity *

Name des Antragstellers *

 

Anrede

E-Mail-Addresse *

 

Telefonnummer *

Department

 

Name der Organisation *

City

Bundesland

Country or Region *

      

Bemerkungen

Massenanfrage

Inquiry Information

Produktname:
Biotinoyl tripeptide-1
Art. -Nr.:
HY-125616
Menge:
MCE Japan Authorized Agent:

Kundenbewertung

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Produktname

  

Lot #

Name des Antragstellers *

 

E-Mail-Addresse *

Telefonnummer

 

Department *

Name der Organisation *

 

Country or Region *

Bemerkungen

SAFETY DATA SHEET (SDS)

English - EN (393 KB) Français - FR (393 KB) Deutsch - DE (393 KB) Norwegian - NO (393 KB) Español - ES (393 KB) Swedish - SV (393 KB) Italian - IT (393 KB) Korean - KR (393 KB) Portuguese - PT (393 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.