2. Neuronal Signaling NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Amyloid-β Reactive Oxygen Species (ROS)
  4. Biotinoyl tripeptide-1

Biotinoyl tripeptide-1  (Synonyms: Biotinyl-GHK; Bio-GHK)

製品番号: HY-125616 純度: 99.02%
COA 取扱説明書 Technical Support

Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases.

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Biotinoyl tripeptide-1

Biotinoyl tripeptide-1 構造式

CAS 番号 : 299157-54-3

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 44 在庫あり
Solution
10 mM * 1 mL in DMSO USD 44 在庫あり
Solid
25 mg $40 在庫あり
50 mg $65 在庫あり
100 mg $110 在庫あり
250 mg $240 在庫あり
500 mg   お問い合わせ  
1 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Biotinoyl tripeptide-1 関連抗体

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製品説明

Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases[1][2].

体外実験

Biotinoyl tripeptide-1 (2 mM) can inhibit the binding of HABA to streptavidin (IC50: 30 µM), indicating that it has a higher affinity for streptavidin[2].
Biotinoyl tripeptide-1 (0-30 μM, 45 min) dose-dependently alters the oxidative activity of ascorbic acid (ASC) induced by Cu-Aβ complexes by coordinating with copper ions and reducing the generation of ROS[2].
Biotinoyl tripeptide-1 (0-120 μM, 100 min) effectively inhibits the production of carbonylated amyloid β in acrolein-induced Aβ1-16[2].
Biotinoyl tripeptide-1 (20 μM, 50 h) inhibits the amyloid aggregation of Aβ in Aβ42[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Biotinoyl tripeptide-1 関連抗体
分子量

566.67

分子式

C24H38N8O6S
CAS 番号
Appearance

Solid

Color

White to off-white

Sequence

{Biotinyl}-Gly-His-Lys
Sequence Shortening

{Biotinyl}-GHK
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 87.5 mg/mL (154.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7647 mL 8.8235 mL 17.6470 mL
5 mM 0.3529 mL 1.7647 mL 3.5294 mL
10 mM 0.1765 mL 0.8823 mL 1.7647 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

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体積 （開始）

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C2

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体積 （終了）

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7647 mL 8.8235 mL 17.6470 mL 44.1174 mL
5 mM 0.3529 mL 1.7647 mL 3.5294 mL 8.8235 mL
10 mM 0.1765 mL 0.8823 mL 1.7647 mL 4.4117 mL
15 mM 0.1176 mL 0.5882 mL 1.1765 mL 2.9412 mL
20 mM 0.0882 mL 0.4412 mL 0.8823 mL 2.2059 mL
25 mM 0.0706 mL 0.3529 mL 0.7059 mL 1.7647 mL
30 mM 0.0588 mL 0.2941 mL 0.5882 mL 1.4706 mL
40 mM 0.0441 mL 0.2206 mL 0.4412 mL 1.1029 mL
50 mM 0.0353 mL 0.1765 mL 0.3529 mL 0.8823 mL
60 mM 0.0294 mL 0.1471 mL 0.2941 mL 0.7353 mL
80 mM 0.0221 mL 0.1103 mL 0.2206 mL 0.5515 mL
100 mM 0.0176 mL 0.0882 mL 0.1765 mL 0.4412 mL
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Biotinoyl tripeptide-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Biotinoyl tripeptide-1299157-54-3Biotinyl-GHK Bio-GHKBiotinoyl tripeptide1Biotinoyl tripeptide 1Amyloid-βReactive Oxygen Species (ROS)β-amyloid peptideAβAbetaBiopeptidesAlzheimer's diseaseantioxidantspeptidesInhibitorinhibitorinhibit

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製品名:
Biotinoyl tripeptide-1
製品番号:
HY-125616
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