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  2. Carmoisine

Carmoisine (Synonyms: Azorubine; Acid Red 14; E122)

Cat. No.: HY-128448
Handling Instructions

Carmoisine (Azorubine) is an azo dye that can be used as a food additive.

For research use only. We do not sell to patients.

Carmoisine Chemical Structure

Carmoisine Chemical Structure

CAS No. : 3567-69-9

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Based on 1 publication(s) in Google Scholar

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Description

Carmoisine (Azorubine) is an azo dye that can be used as a food additive[1][2].

In Vitro

Carmoisine augments the in vitro synthesis of leukotriene B4 (LTB4) and F2-isoprostanes from blood neutrophils. Carmoisine increases the formation of F2-isoprostanes from blood neutrophils at all tested concentrations[2].

In Vivo

Carmoisine (49.3-493 mg/kg; oral administration; for 42 days; male Wistar rats) treatment increases MAPK8 expression at remarkably low and high concentrations, the expression of NFκB and GADD45α does not change[1].

Animal Model: Male Wistar rats (120-300 g)[1]
Dosage: 49.3 mg/kg, 493 mg/kg
Administration: Oral administration; for 42 days
Result: Resulted in apoptosis according to MAPK8 expression.
Molecular Weight

502.43

Formula

C₂₀H₁₂N₂Na₂O₇S₂

CAS No.

3567-69-9

SMILES

O=S(C1=C2C=CC=CC2=C(O)C(/N=N/C3=C4C=CC=CC4=C(S(=O)(O[Na])=O)C=C3)=C1)(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (99.52 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9903 mL 9.9516 mL 19.9033 mL
5 mM 0.3981 mL 1.9903 mL 3.9807 mL
10 mM 0.1990 mL 0.9952 mL 1.9903 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

CarmoisineAzorubineAcid Red 14E122Acid Red14Acid Red-14E 122E-122OthersArtificialcolorantfoodadditiveMAPK8azoproinflammatoryInhibitorinhibitorinhibit

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Carmoisine
Cat. No.:
HY-128448
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