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  3. Carmoisine

Carmoisine  (Synonyms: Azorubine; Acid Red 14; E122)

Art. -Nr.: HY-128448 Reinheit: 98.66%
Handling Instructions Technical Support

Carmoisine (Azorubine) is an azo dye that can be used as a food additive.

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Carmoisine

Carmoisine Chemische Struktur

CAS. Nr. : 3567-69-9

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
Solid
100 mg Auf Lager
500 mg Auf Lager
1 g Auf Lager
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10 g   Angebot einholen  

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Beschreibung

Carmoisine (Azorubine) is an azo dye that can be used as a food additive[1][2].

In Vitro

Carmoisine augments the in vitro synthesis of leukotriene B4 (LTB4) and F2-isoprostanes from blood neutrophils. Carmoisine increases the formation of F2-isoprostanes from blood neutrophils at all tested concentrations[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Carmoisine (49.3-493 mg/kg; oral administration; for 42 days; male Wistar rats) treatment increases MAPK8 expression at remarkably low and high concentrations, the expression of NFκB and GADD45α does not change[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rats (120-300 g)[1]
Dosage: 49.3 mg/kg, 493 mg/kg
Administration: Oral administration; for 42 days
Result: Resulted in apoptosis according to MAPK8 expression.
Klinische Studie
Molekulargewicht

502.43

Formel

C20H12N2Na2O7S2

CAS. Nr.
Appearance

Solid

Color

Brown to black

SMILES

O=S(C1=C2C=CC=CC2=C(O)C(/N=N/C3=C4C=CC=CC4=C(S(=O)(O[Na])=O)C=C3)=C1)(O[Na])=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 50 mg/mL (99.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9903 mL 9.9516 mL 19.9033 mL
5 mM 0.3981 mL 1.9903 mL 3.9807 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 98.66%

Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9903 mL 9.9516 mL 19.9033 mL 49.7582 mL
5 mM 0.3981 mL 1.9903 mL 3.9807 mL 9.9516 mL
10 mM 0.1990 mL 0.9952 mL 1.9903 mL 4.9758 mL
15 mM 0.1327 mL 0.6634 mL 1.3269 mL 3.3172 mL
20 mM 0.0995 mL 0.4976 mL 0.9952 mL 2.4879 mL
25 mM 0.0796 mL 0.3981 mL 0.7961 mL 1.9903 mL
30 mM 0.0663 mL 0.3317 mL 0.6634 mL 1.6586 mL
40 mM 0.0498 mL 0.2488 mL 0.4976 mL 1.2440 mL
50 mM 0.0398 mL 0.1990 mL 0.3981 mL 0.9952 mL
60 mM 0.0332 mL 0.1659 mL 0.3317 mL 0.8293 mL
80 mM 0.0249 mL 0.1244 mL 0.2488 mL 0.6220 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Produktname:
Carmoisine
Art. -Nr.:
HY-128448
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