2. Others Neuronal Signaling Autophagy Immunology/Inflammation NF-κB GPCR/G Protein Apoptosis PI3K/Akt/mTOR
  3. p62 Pyroptosis Autophagy Keap1-Nrf2 mTOR Reference Standards mAChR Histamine Receptor IKK Apoptosis
  4. Clemastine fumarate (Standard)

Clemastine fumarate (Standard)  (Synonyms: HS-592 fumarate (Standard); Meclastine fumarate (Standard))

製品番号: HY-B0298AR 純度: 98%
取扱説明書 Technical Support

Clemastine (HS-592; Meclastine) fumarate (Standard) is the analytical standard of Clemastine fumarate. This product is intended for research and analytical applications. Clemastine fumarate is an orally active, blood-brain barrier-permeable H1 histamine receptor (H1 histamine receptor) antagonist with potent antiallergic effects. Clemastine fumarate also antagonizes muscarinic acetylcholine receptors (mAChR), particularly the M1 and M4 subtypes. In addition to antihistamine effects, Clemastine fumarate exhibits multiple pharmacological activities, especially in promoting central nervous system remyelination, activating autophagy and pyroptosis, exerting anti-apoptotic and neuroprotective effects, and suppressing inflammation .

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Clemastine fumarate (Standard)

Clemastine fumarate (Standard) 構造式

CAS 番号 : 14976-57-9

容量 価格（税別） 在庫状況 数量
5 mg $30 お問い合わせ 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
10 mg $45 お問い合わせ 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
25 mg $77 お問い合わせ 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
50 mg $111 お問い合わせ 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
100 mg $156 お問い合わせ 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
200 mg   お問い合わせ  
500 mg   お問い合わせ  
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製品説明

Clemastine (HS-592; Meclastine) fumarate (Standard) is the analytical standard of Clemastine fumarate. This product is intended for research and analytical applications. Clemastine fumarate is an orally active, blood-brain barrier-permeable H1 histamine receptor (H1 histamine receptor) antagonist with potent antiallergic effects. Clemastine fumarate also antagonizes muscarinic acetylcholine receptors (mAChR), particularly the M1 and M4 subtypes. In addition to antihistamine effects, Clemastine fumarate exhibits multiple pharmacological activities, especially in promoting central nervous system remyelination, activating autophagy and pyroptosis, exerting anti-apoptotic and neuroprotective effects, and suppressing inflammation .

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
分子量

459.96

分子式

C25H30ClNO5
CAS 番号
SMILES

CN1[C@@H](CCO[C@](C2=CC=CC=C2)(C3=CC=C(Cl)C=C3)C)CCC1.O=C(O)/C=C/C(O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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Clemastine fumarate (Standard) Related Classifications

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Keywords:

Clemastine fumarate (Standard)14976-57-9HS-592 fumarate (Standard) Meclastine fumarate (Standard)p62PyroptosisAutophagyKeap1-Nrf2mTORReference StandardsmAChRHistamine ReceptorIKKApoptosisSequestosome-1SQSTM1Mammalian target of RapamycinMuscarinic acetylcholine receptorIκB kinaseI kappa B kinase Inhibitorinhibitorinhibit

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製品名:
Clemastine fumarate (Standard)
製品番号:
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