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Copper tripeptide  (Synonyms: GHK-Cu)

製品番号: HY-P0063 純度: 99.85%
COA 取扱説明書 Technical Support

Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration.

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Copper tripeptide

Copper tripeptide 構造式

CAS 番号 : 89030-95-5

容量 価格(税別) 在庫状況 数量
100 mg $55 在庫あり
250 mg $90 在庫あり
500 mg $130 在庫あり
1 g   お問い合わせ  
5 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Copper tripeptide:

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製品説明

Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration[1].

体外実験

Copper tripeptide (1 nM; 0-96 hours) affects irradiated fibroblasts such that their population-doubling times approximated that of controls[1].
Copper tripeptide (1 nM; 0-120 hours) significantly produces more basic fibroblast growth factors than normal controls at a 24-hour interval of irradiated fibroblasts[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

臨床実験
分子量

401.91

分子式

C14H22CuN6O4

CAS 番号
Appearance

Solid

Color

Blue to purple

Sequence

Gly-His-Lys-Cu

Sequence Shortening

GHK-Cu

Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

polypeptide, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (polypeptide, sealed storage, away from moisture and light)

溶剤 & 溶解度
体外: 

H2O : 50 mg/mL (124.41 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4881 mL 12.4406 mL 24.8812 mL
5 mM 0.4976 mL 2.4881 mL 4.9762 mL
10 mM 0.2488 mL 1.2441 mL 2.4881 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

×
体積 (終了)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.85%

参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4881 mL 12.4406 mL 24.8812 mL 62.2030 mL
5 mM 0.4976 mL 2.4881 mL 4.9762 mL 12.4406 mL
10 mM 0.2488 mL 1.2441 mL 2.4881 mL 6.2203 mL
15 mM 0.1659 mL 0.8294 mL 1.6587 mL 4.1469 mL
20 mM 0.1244 mL 0.6220 mL 1.2441 mL 3.1101 mL
25 mM 0.0995 mL 0.4976 mL 0.9952 mL 2.4881 mL
30 mM 0.0829 mL 0.4147 mL 0.8294 mL 2.0734 mL
40 mM 0.0622 mL 0.3110 mL 0.6220 mL 1.5551 mL
50 mM 0.0498 mL 0.2488 mL 0.4976 mL 1.2441 mL
60 mM 0.0415 mL 0.2073 mL 0.4147 mL 1.0367 mL
80 mM 0.0311 mL 0.1555 mL 0.3110 mL 0.7775 mL
100 mM 0.0249 mL 0.1244 mL 0.2488 mL 0.6220 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
Copper tripeptide
製品番号:
HY-P0063
数量:
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