Copper tripeptide acetate
Based on 1 publication(s) in Google Scholar
Copper tripeptide (GHK-Cu) acetate is a tripeptide. During wound healing, Copper tripeptide acetate may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide acetate has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide acetate is a natural modulator of multiple cllular pathways in skin regeneration.
For research use only. We do not sell to patients.
- CAS No.: 300801-03-0
- Formula: C16H26CuN6O6
- Molecular Weight:461.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Copper tripeptide acetate
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Biological Activity
Description
In Vitro
Copper tripeptide (1 nM; 0-96 hours) acetate affects irradiated fibroblasts such that their population-doubling times approximated that of controls[1]. Copper tripeptide (1 nM; 0-120 hours) acetate significantly produces more basic fibroblast growth factors than normal controls at a 24-hour interval of irradiated fibroblasts[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 300801-03-0
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Molecular Weight 461.96
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Formula C16H26CuN6O6
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SMILES
CC(O)=O.NCCCC[C@@H](C([O-])=O)NC([C@H]1[N-]2[Cu+2]([NH2]CC2=O)[N]3=CNC=C3C1)=O
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Synonyms
GHK-Cu acetate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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J Appl Toxicol
Copper induces oxidative stress and apoptosis of hippocampal neuron via pCREB/BDNF/ and Nrf2/HO-1/NQO1 pathway. [Abstract]2022 Apr;42(4):694-705. PMID: 34676557
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)