Cyclopenthiazide

Name: Cyclopenthiazide
Brand: MedChemExpress
SKU: HY-109542
Rating: 4.5 (0 reviews)

Cat. No.: HY-109542 Purity: 98.40%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Cyclopenthiazide is a benzothiadiazine diuretic with antihypertensive properties. Cyclopenthiazide exerts a diuretic effect by inhibiting the reabsorption of sodium chloride and water at the distal renal tubules. Cyclopenthiazide increases the excretory capacity of the rat kidney.

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Cyclopenthiazide 화학구조

CAS No. : 742-20-1

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Cyclopenthiazide:

Cyclopenthiazide (Standard) 견적 받기

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

In Vivo

Cyclopenthiazide (0.5 mg/kg; i.p.; daily, for 3 days; female Wistar rats) increases the excretion of p-aminohippurate (PAH) ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female Wistar rats^[1]
Dosage:	0.5 mg/kg
Administration:	Intraperitoneal injection; daily, for 3 days
Result:	Stimulated p-aminohippurate (PAH) excretion.

분자량

379.88

화학식

C₁₃H₁₈ClN₃O₄S₂

CAS No.

742-20-1

Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=C(Cl)C=C(C2=C1)NC(CC3CCCC3)NS2(=O)=O)(N)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도

In Vitro:

DMSO : 125 mg/mL (329.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6324 mL	13.1621 mL	26.3241 mL
5 mM	0.5265 mL	2.6324 mL	5.2648 mL
10 mM	0.2632 mL	1.3162 mL	2.6324 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.40%

Select Batch:

Data Sheet (273 KB) SDS (392 KB)

COA (251 KB) HNMR (275 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Bräunlich H. Postnatal development of kidney function in rats receiving thyroid hormones. Exp Clin Endocrinol. 1984 May;83(3):243-50. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6324 mL	13.1621 mL	26.3241 mL	65.8103 mL
	5 mM	0.5265 mL	2.6324 mL	5.2648 mL	13.1621 mL
	10 mM	0.2632 mL	1.3162 mL	2.6324 mL	6.5810 mL
	15 mM	0.1755 mL	0.8775 mL	1.7549 mL	4.3874 mL
	20 mM	0.1316 mL	0.6581 mL	1.3162 mL	3.2905 mL
	25 mM	0.1053 mL	0.5265 mL	1.0530 mL	2.6324 mL
	30 mM	0.0877 mL	0.4387 mL	0.8775 mL	2.1937 mL
	40 mM	0.0658 mL	0.3291 mL	0.6581 mL	1.6453 mL
	50 mM	0.0526 mL	0.2632 mL	0.5265 mL	1.3162 mL
	60 mM	0.0439 mL	0.2194 mL	0.4387 mL	1.0968 mL
	80 mM	0.0329 mL	0.1645 mL	0.3291 mL	0.8226 mL
	100 mM	0.0263 mL	0.1316 mL	0.2632 mL	0.6581 mL