2. Anticuerpos inhibidores
  3. Functional Proteins
  4. Epoetin beta

Epoetin beta  (Synonyms: rhEPO; EPOCH; Genetical recombination)

Cat. No.: HY-114134 Pureza: ≥95.0%
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Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta is responsible for the maintenance of erythropoiesis and can be used for anaemia research.

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No. CAS : 122312-54-3

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Epoetin beta Related Antibodies

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Descripciòn

Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta is responsible for the maintenance of erythropoiesis and can be used for anaemia research[1].

In Vivo

Epoetin beta (rhEPO) (1000 IU/kg; s.c.; three times per week over 14 days) prevents anaemia and enhances the radiosensitivity of solid growing DS-sarcomas[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats, body weight 140-170 g[2]
Dosage: 1000 IU/kg
Administration: Subcutaneous injection, three times per week over 14 days starting 9 days before tumour implantation. Solid DS-sarcomas were induced by injecting DS-sarcoma cells (0.4 mL, approximately 104 cells/uL) subcutaneously into the hind food dorsum. A prolonged anaemia was induced in all animals by a single i.v. dose of carboplatin (45 mg/kg dissolved in isotonic saline at a concentration of 20 mg/mL) into the tail vein 3 days before tumour implantation.
Result: Prevented anaemia and significantly increased the radiosensitivity of solid growing DS-sarcomas, tumours showing pronounced hypoxia even under non-anaemic control conditions.
Ensayo clínico
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Peso molecular

60 kDa

No. CAS
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Epoetin beta]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • EPO
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Epoetin beta Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epoetin beta122312-54-3rhEPO EPOCH Genetical recombinationOthersanaemiahaemoglobinhaematocritreticulocyte countserythropoietinInhibitorinhibitorinhibit

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Nombre del producto:
Epoetin beta
Cat. No.:
HY-114134
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