2. Others Protein Tyrosine Kinase/RTK JAK/STAT Signaling Autophagy
  3. Reference Standards EGFR Autophagy
  4. Erlotinib (Standard)

Erlotinib (Standard)  (Synonyms: CP-358774 (Standard); NSC 718781 (Standard); OSI-774 (Standard))

Cat. No.: HY-50896R Pureza: 99.97%
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Erlotinib (Standard) is the analytical standard of Erlotinib. This product is intended for research and analytical applications. Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Erlotinib (Standard)

Erlotinib (Standard) Estructura química

No. CAS : 183321-74-6

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Information
Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Peso molecular

393.44

Fòrmula

C22H23N3O4
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

C#CC1=CC=CC(NC2=NC=NC3=C2C=C(C(OCCOC)=C3)OCCOC)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Erlotinib (Standard) Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Erlotinib (Standard)183321-74-6CP-358774 (Standard)NSC 718781 (Standard)OSI-774 (Standard)Reference StandardsEGFRAutophagyEpidermal growth factor receptorErbB-1HER1directlyactingautophosphorylationintacttumornon-smallcelllungcancerInhibitorinhibitorinhibit

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Nombre del producto:
Erlotinib (Standard)
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HY-50896R
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