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Ethylene glycol is an organic compound that is often used as an antifreeze agent and coolant. Ethylene glycol lowers the freezing point by forming hydrogen bonds with water molecules, exerting antifreeze activity. Ethylene glycol is also used as a raw material in the synthesis of polymers such as polyester fibers and polyurethanes.

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Ethylene glycol,98%

Ethylene glycol,98% Chemische Struktur

CAS. Nr. : 107-21-1

Größe Preis Verfügbarkeit Menge
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
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Beschreibung

Ethylene glycol is an organic compound that is often used as an antifreeze agent and coolant. Ethylene glycol lowers the freezing point by forming hydrogen bonds with water molecules, exerting antifreeze activity. Ethylene glycol is also used as a raw material in the synthesis of polymers such as polyester fibers and polyurethanes[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Cellular Effect
Cell Line Type Value Description References
HL-60 CC50
221 3
Compound: 1,2-ethanediol
Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test
Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test
[PMID: 17499885]
HL-60 CC50
221 3
Compound: 1,2-ethanediol
Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test
Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test
[PMID: 17499885]
HL-60 CC50
221 3
Compound: 1,2-ethanediol
Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test
Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test
[PMID: 17499885]
HSC-2 CC50
> 400 3
Compound: 1,2-ethanediol
Cytotoxicity against human HSC2 by MTT method
Cytotoxicity against human HSC2 by MTT method
[PMID: 17499885]
HSC-2 CC50
> 400 3
Compound: 1,2-ethanediol
Cytotoxicity against human HSC2 by MTT method
Cytotoxicity against human HSC2 by MTT method
[PMID: 17499885]
HSC-2 CC50
>400 3
Compound: 1,2-ethanediol
Cytotoxicity against human HSC2 by MTT method
Cytotoxicity against human HSC2 by MTT method
[PMID: 17499885]
HSC-4 CC50
385 3
Compound: 1,2-ethanediol
Cytotoxicity against human HSC4 cells by MTT method
Cytotoxicity against human HSC4 cells by MTT method
[PMID: 17499885]
HSC-4 CC50
385 3
Compound: 1,2-ethanediol
Cytotoxicity against human HSC4 cells by MTT method
Cytotoxicity against human HSC4 cells by MTT method
[PMID: 17499885]
HSC-4 CC50
385 3
Compound: 1,2-ethanediol
Cytotoxicity against human HSC4 cells by MTT method
Cytotoxicity against human HSC4 cells by MTT method
[PMID: 17499885]
In Vitro

Ethylene glycol, 98% In nanomaterial synthesis experiments, it acts as a solvent and reducing agent to promote the formation of monodisperse metal nanocrystals (such as silver nanorods, Cu2O nanocubes) by reducing metal ions (such as Ag+, Cu2+) [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

62.07

Formel

C2H6O2

CAS. Nr.
Appearance

Liquid (Density: 1.113 g/cm3)

Color

Colorless to light yellow

SMILES

OCCO

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : ≥ 100 mg/mL (1611.08 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 16.1108 mL 80.5542 mL 161.1084 mL
5 mM 3.2222 mL 16.1108 mL 32.2217 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 99.9%

Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 16.1108 mL 80.5542 mL 161.1084 mL 402.7711 mL
5 mM 3.2222 mL 16.1108 mL 32.2217 mL 80.5542 mL
10 mM 1.6111 mL 8.0554 mL 16.1108 mL 40.2771 mL
15 mM 1.0741 mL 5.3703 mL 10.7406 mL 26.8514 mL
20 mM 0.8055 mL 4.0277 mL 8.0554 mL 20.1386 mL
25 mM 0.6444 mL 3.2222 mL 6.4443 mL 16.1108 mL
30 mM 0.5370 mL 2.6851 mL 5.3703 mL 13.4257 mL
40 mM 0.4028 mL 2.0139 mL 4.0277 mL 10.0693 mL
50 mM 0.3222 mL 1.6111 mL 3.2222 mL 8.0554 mL
60 mM 0.2685 mL 1.3426 mL 2.6851 mL 6.7129 mL
80 mM 0.2014 mL 1.0069 mL 2.0139 mL 5.0346 mL
100 mM 0.1611 mL 0.8055 mL 1.6111 mL 4.0277 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ethylene glycol,98%
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