Ethylene Glycol-d₆

Name: Ethylene Glycol-d 6
Brand: MedChemExpress
SKU: HY-Y0338S3
Rating: 4.5 (1 reviews)

Cat. No.: HY-Y0338S3 Purity: 99.95%: Data Sheet
COA

SDS
Handling Instructions
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Ethylene Glycol-d₆ is the deuterium labeled Ethylene glycol[1].

For research use only. We do not sell to patients.

Ethylene Glycol-d₆ Chemical Structure

CAS No. : 15054-86-1

Size	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Liquid
1 mg	Get quote	Estimated Time of Arrival: December 31
50 mg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
100 mg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
250 mg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ethylene Glycol-d₆:

Ethylene glycol,98% In-stock

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Biological Activity
Purity & Documentation
References
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Description

Ethylene Glycol-d₆ is the deuterium labeled Ethylene glycol[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

68.10

Formula

C₂D₆O₂

CAS No.

15054-86-1

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[2H]OC([2H])([2H])C([2H])([2H])O[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL (2936.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	14.6843 mL	73.4214 mL	146.8429 mL
5 mM	2.9369 mL	14.6843 mL	29.3686 mL
10 mM	1.4684 mL	7.3421 mL	14.6843 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

Select Batch:

Data Sheet (271 KB) SDS (557 KB)

COA (250 KB) HNMR (125 KB) GC (233 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	14.6843 mL	73.4214 mL	146.8429 mL	367.1072 mL
	5 mM	2.9369 mL	14.6843 mL	29.3686 mL	73.4214 mL
	10 mM	1.4684 mL	7.3421 mL	14.6843 mL	36.7107 mL
	15 mM	0.9790 mL	4.8948 mL	9.7895 mL	24.4738 mL
	20 mM	0.7342 mL	3.6711 mL	7.3421 mL	18.3554 mL
	25 mM	0.5874 mL	2.9369 mL	5.8737 mL	14.6843 mL
	30 mM	0.4895 mL	2.4474 mL	4.8948 mL	12.2369 mL
	40 mM	0.3671 mL	1.8355 mL	3.6711 mL	9.1777 mL
	50 mM	0.2937 mL	1.4684 mL	2.9369 mL	7.3421 mL
	60 mM	0.2447 mL	1.2237 mL	2.4474 mL	6.1185 mL
	80 mM	0.1836 mL	0.9178 mL	1.8355 mL	4.5888 mL
	100 mM	0.1468 mL	0.7342 mL	1.4684 mL	3.6711 mL