2. Anti-infection
  3. Beta-lactamase Bacterial
  4. Funobactam

Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria.

Para uso exclusivo en investigación. No vendemos a pacientes.

Funobactam

Funobactam Estructura química

No. CAS : 2365454-12-0

Tamaño Precio Stock Cantidad
1 mg En stock
5 mg En stock
10 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

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Funobactam Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas Beta-lactamase:

Ver todas las isoformas
Metallo-β-lactamase (MBL) Serine β-lactamase (SBL)

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

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Descripciòn

Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria[1].

IC50 & Target

β-lactamase[1]
In Vitro

Funobactam has no intrinsic antibacterial activity and is commonly used in combination with imipenem[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Funobactam Related Antibodies
In Vivo

Funobactam (1, 10, and 20 mg/kg, s.c., single-dose) has protein-binding percentage values of 3.11% , 5.44%  , and 2.03% in the presence of imipenem HSR [3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Ensayo clínico
Peso molecular

399.38

Fòrmula

C13H17N7O6S
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=S(ON1[C@@H]2C3(CC3)C[C@](C4=NN=C([C@@]5([H])NC(N)=NC5)O4)([H])[N@](C1=O)C2)(O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 25 mg/mL (62.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5039 mL 12.5194 mL 25.0388 mL
5 mM 0.5008 mL 2.5039 mL 5.0078 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.47%

SDS (251 KB)

COA (254 KB) HNMR (267 KB) LCMS (87 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5039 mL 12.5194 mL 25.0388 mL 62.5970 mL
5 mM 0.5008 mL 2.5039 mL 5.0078 mL 12.5194 mL
10 mM 0.2504 mL 1.2519 mL 2.5039 mL 6.2597 mL
15 mM 0.1669 mL 0.8346 mL 1.6693 mL 4.1731 mL
20 mM 0.1252 mL 0.6260 mL 1.2519 mL 3.1299 mL
25 mM 0.1002 mL 0.5008 mL 1.0016 mL 2.5039 mL
30 mM 0.0835 mL 0.4173 mL 0.8346 mL 2.0866 mL
40 mM 0.0626 mL 0.3130 mL 0.6260 mL 1.5649 mL
50 mM 0.0501 mL 0.2504 mL 0.5008 mL 1.2519 mL
60 mM 0.0417 mL 0.2087 mL 0.4173 mL 1.0433 mL
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Funobactam Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Funobactam2365454-12-0XNW4107XNW 4107XNW-4107Beta-lactamaseBacterialβ-lactamaseantibacterialInhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
Funobactam
Cat. No.:
HY-147274
Cantidad:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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