1. Anti-infection
  2. Beta-lactamase Bacterial
  3. Funobactam

Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria.

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Funobactam

Funobactam 화학구조

CAS No. : 2365454-12-0

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

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Top Publications Citing Use of Products

View All Beta-lactamase Isoform Specific Products:

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria[1].

IC50 & Target

β-lactamase[1]

In Vitro

Funobactam has no intrinsic antibacterial activity and is commonly used in combination with imipenem[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Funobactam (1, 10, and 20 mg/kg, s.c., single-dose) has protein-binding percentage values of 3.11% , 5.44%  , and 2.03% in the presence of imipenem HSR [3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
분자량

399.38

화학식

C13H17N7O6S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(ON1[C@@H]2C3(CC3)C[C@](C4=NN=C([C@@]5([H])NC(N)=NC5)O4)([H])[N@](C1=O)C2)(O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 25 mg/mL (62.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5039 mL 12.5194 mL 25.0388 mL
5 mM 0.5008 mL 2.5039 mL 5.0078 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 99.47%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5039 mL 12.5194 mL 25.0388 mL 62.5970 mL
5 mM 0.5008 mL 2.5039 mL 5.0078 mL 12.5194 mL
10 mM 0.2504 mL 1.2519 mL 2.5039 mL 6.2597 mL
15 mM 0.1669 mL 0.8346 mL 1.6693 mL 4.1731 mL
20 mM 0.1252 mL 0.6260 mL 1.2519 mL 3.1299 mL
25 mM 0.1002 mL 0.5008 mL 1.0016 mL 2.5039 mL
30 mM 0.0835 mL 0.4173 mL 0.8346 mL 2.0866 mL
40 mM 0.0626 mL 0.3130 mL 0.6260 mL 1.5649 mL
50 mM 0.0501 mL 0.2504 mL 0.5008 mL 1.2519 mL
60 mM 0.0417 mL 0.2087 mL 0.4173 mL 1.0433 mL
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Funobactam Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

상품명:
Funobactam
Cat. No.:
HY-147274
수량:
MCE Japan Authorized Agent: