NMS - neuromedin S Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 129521

About NMS

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:100,470,482-100,483,280 (from NCBI)

This gene has 1 transcript (splice variant) and 86 orthologues. Low expression observed in reference dataset.

Summary

This gene encodes a member of the neuromedin family of neuropeptides. The encoded preproprotein is proteolytically processed to generate a biologically active neuropeptide that plays a role in the regulation of circadian rhythm, anorexigenic action, antidiuretic action, cardiovascular function and stimulation of oxytocin and vasopressin release. [provided by RefSeq, May 2016]

NMS Products (1)

mRNA Protein Name
NM_001011717.1 NP_001011717.1 neuromedin-S preproprotein
Protein Preferred Names Protein Names

neuromedin-S

  • neuromedin S precursor-related peptide/neuromedin S preproprotein

Related Diseases

Diseases Alias
Type 1 Diabetes Mellitus 2

  • Diabetes Mellitus, Noninsulin-Dependent, 1

  • Diabetes Mellitus, Insulin-Dependent, 2

  • IDDM2

  • Insulin-Dependent Diabetes Mellitus 2

  • NIDDM1

  • Diabetes Mellitus, Noninsulin-Dependent 1

  • T1D2

  • Type 2 Diabetes Mellitus 1

  • T2D1

  • Noninsulin-Dependent Diabetes Mellitus 1

  • Diabetes Mellitus, Non-Insulin-Dependent, 1

  • Type 2 Diabetes Mellitus 1, Susceptibility To

  • Diabetes Mellitus, Insulin-Dependent, Type 2

  • Diabetes Mellitus, Non-Insulin-Dependent
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12678 Entrectinib 99.26% Yes
HY-B0267A Oxybutynin chloride 98.49% Yes
HY-B0267AR Oxybutynin chloride (Standard) / Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-15828 Onvansertib 99.86% Phase 2

Pre-clinical Phase

Bioactive Molecules (25)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15713 NMS-873 Inhibitor 99.92% Unkown
HY-12382 NMS-P715 Inhibitor 99.30% Unkown
HY-17547 NMS-E973 Inhibitor 99.61% Unkown
HY-15714 NMS-859 Inhibitor 98.02% Unkown
HY-18954 NMS-P118 Inhibitor 99.54% Unkown
HY-176533 S1PR5-IN-1 Inhibitor 99.58% Unkown
HY-122203 PCS1055 dihydrochloride 98.88% Unkown
HY-12678S1 Entrectinib-d8 99.82% Unkown
HY-128599 NMS-P515 Inhibitor 98.18% Unkown
HY-122203A PCS1055 98.02% Unkown
HY-171138 Mal-VC-PAB-DMEA-PNU-159682 99.36% Unkown
HY-168979 Itareparib Inhibitor 99.24% Unkown
HY-12678S Entrectinib-d4 Inhibitor / Unkown
HY-185427 Opugotamig olatansine Modulator / Unkown
HY-117744 NMS-P645 Inhibitor / Unkown
HY-156249 NMS-P528 / Unkown
HY-156299 NMS-P945 / Unkown
HY-162427 NMS-0963 Inhibitor / Unkown
HY-180358 Gallamine / Unkown
HY-RS09388 NMS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-116470 Mps1/TTK-IN-1 Inhibitor / Unkown
HY-129679 NMS-P953 Inhibitor / Unkown
HY-164514 NMS-P626 Inhibitor / Unkown
HY-RS18899 Nms Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25390 Nms Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NMS MGD MGI:3583618
Bos taurus NMS VGNC VGNC:32136
Rattus norvegicus NMS RGD RGD:1359122
Canis familiaris NMS VGNC VGNC:108209
Macaca mulatta NMS VGNC VGNC:75289
Others NMS NCBI