NMS - neuromedin S Gene

Homo sapiens

Gene ID: 129521 | Gene type: protein coding

About NMS

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:100,470,482-100,483,280 (from NCBI)

This gene has 1 transcript (splice variant) and 86 orthologues. Low expression observed in reference dataset.

Summary

This gene encodes a member of the neuromedin family of neuropeptides. The encoded preproprotein is proteolytically processed to generate a biologically active neuropeptide that plays a role in the regulation of circadian rhythm, anorexigenic action, antidiuretic action, cardiovascular function and stimulation of oxytocin and vasopressin release. [provided by RefSeq, May 2016]

NMS Products(1)

mRNA	Protein	Name
NM_001011717.1	NP_001011717.1	neuromedin-S preproprotein

Protein Preferred Names

Protein Names

neuromedin-S

neuromedin S precursor-related peptide/neuromedin S preproprotein

Related Diseases

Diseases

Alias

Type 1 Diabetes Mellitus 2

Diabetes Mellitus, Noninsulin-Dependent, 1	Diabetes Mellitus, Insulin-Dependent, 2
IDDM2	Insulin-Dependent Diabetes Mellitus 2
NIDDM1	Diabetes Mellitus, Noninsulin-Dependent 1
T1D2	Type 2 Diabetes Mellitus 1
T2D1	Noninsulin-Dependent Diabetes Mellitus 1
Diabetes Mellitus, Non-Insulin-Dependent, 1	Type 2 Diabetes Mellitus 1, Susceptibility To
Diabetes Mellitus, Insulin-Dependent, Type 2	Diabetes Mellitus, Non-Insulin-Dependent

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-12678	Entrectinib	99.87%	Yes
HY-B0267A	Oxybutynin chloride	99.15%	Yes
HY-B0267AR	Oxybutynin chloride (Standard)	/	Unkown

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-15828	Onvansertib		99.55%	Phase 2

Pre-clinical Phase

Bioactive Molecules (13)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15713	NMS-873	Inhibitor	99.87%	Unkown
HY-12382	NMS-P715	Inhibitor	98.41%	Unkown
HY-18954	NMS-P118	Inhibitor	99.78%	Unkown
HY-17547	NMS-E973	Inhibitor	98.57%	Unkown
HY-15714	NMS-859	Inhibitor	98.05%	Unkown
HY-128599	NMS-P515	Inhibitor	98.18%	Unkown
HY-12678S	Entrectinib-d4	Inhibitor	/	Unkown
HY-122203	PCS1055 dihydrochloride		/	Unkown
HY-12678S1	Entrectinib-d8		99.82%	Unkown
HY-156249	NMS-P528		/	Unkown
HY-156299	NMS-P945		/	Unkown
HY-162427	NMS-0963	Inhibitor	/	Unkown
HY-RS09388	NMS Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NMS	MGD	MGI:3583618
Bos taurus	NMS	VGNC	VGNC:32136
Rattus norvegicus	NMS	RGD	RGD:1359122
Canis familiaris	NMS	VGNC	VGNC:108209
Macaca mulatta	NMS	VGNC	VGNC:75289

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