GLP-1 receptor agonist 7

Cat. No.: HY-145412 Purity: 98.01%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

GLP-1 receptor agonist 7 (Compound 130b) is a potent agonist of glucagon-like peptide-1 (GLP-1). GLP-1 receptor agonist 7 generates cAMP under the mediation of GLP-1R with an EC₅₀ of ≤ 0.2 nM. GLP-1 receptor agonist 7 can be used to study diseases related to the GLP-1 receptor (particularly type 2 diabetes).

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GLP-1 receptor agonist 7 화학구조

CAS No. : 2736447-04-2

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	견적 받기
200 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

IC₅₀ & Target

GLP-1^[1]

분자량

593.05

화학식

C₃₁H₃₀ClFN₄O₅

CAS No.

2736447-04-2

Appearance

Solid

Color

White to light yellow

SMILES

OC(C1=CC=C2C(N(C(CN3CCC(C4=C(O[C@](C(C=CC(Cl)=C5)=C5F)([H])CO6)C6=CC=C4)CC3)=N2)C[C@@H]7CCO7)=N1)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도

In Vitro:

DMSO : 125 mg/mL (210.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6862 mL	8.4310 mL	16.8620 mL
5 mM	0.3372 mL	1.6862 mL	3.3724 mL
10 mM	0.1686 mL	0.8431 mL	1.6862 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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순도&문서

Purity: 98.17%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (255 KB) HNMR (304 KB) RP-HPLC (225 KB) MS (70 KB)

Handling Instructions (2659 KB)

References

[1]. Qinghua Meng, et al. Heterocyclic glp-1 agonists. Patent WO2021219019A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6862 mL	8.4310 mL	16.8620 mL	42.1550 mL
	5 mM	0.3372 mL	1.6862 mL	3.3724 mL	8.4310 mL
	10 mM	0.1686 mL	0.8431 mL	1.6862 mL	4.2155 mL
	15 mM	0.1124 mL	0.5621 mL	1.1241 mL	2.8103 mL
	20 mM	0.0843 mL	0.4215 mL	0.8431 mL	2.1077 mL
	25 mM	0.0674 mL	0.3372 mL	0.6745 mL	1.6862 mL
	30 mM	0.0562 mL	0.2810 mL	0.5621 mL	1.4052 mL
	40 mM	0.0422 mL	0.2108 mL	0.4215 mL	1.0539 mL
	50 mM	0.0337 mL	0.1686 mL	0.3372 mL	0.8431 mL
	60 mM	0.0281 mL	0.1405 mL	0.2810 mL	0.7026 mL
	80 mM	0.0211 mL	0.1054 mL	0.2108 mL	0.5269 mL
	100 mM	0.0169 mL	0.0843 mL	0.1686 mL	0.4215 mL