Gly-Gly-Gly-PEG3-TCO

Name: Gly-Gly-Gly-PEG3-TCO
Brand: MedChemExpress
SKU: HY-141190
Rating: 4.5 (0 reviews)

製品番号: HY-141190 純度: 99.90%: Data Sheet SDS COA 取扱説明書
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Gly-Gly-Gly-PEG3-TCO is a 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Gly-Gly-Gly-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

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Gly-Gly-Gly-PEG3-TCO 構造式

CAS 番号 : 2353409-81-9

容量	価格（税別）	在庫状況	数量
1 mg	$200	在庫あり	Estimated Time of Arrival: December 31
5 mg	$590	在庫あり	Estimated Time of Arrival: December 31
10 mg		お問い合わせ
50 mg		お問い合わせ

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カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of Gly-Gly-Gly-PEG3-TCO:

Gly-Gly-Gly-PEG3-TCO TFA お問い合わせ

ADC Linker アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Gly-Gly-Gly-PEG3-TCO is a 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1]. Gly-Gly-Gly-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

体外実験

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

515.60

分子式

C₂₃H₄₁N₅O₈

CAS 番号

2353409-81-9

Appearance

Oil

Color

Off-white to light yellow

SMILES

NCC(NCC(NCC(NCCOCCOCCOCCNC(OC1CC/C=C\CCC1)=O)=O)=O)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

純度とドキュメンテーション

純度: 99.90%

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データシート (262 KB) SDS (393 KB)

COA (241 KB) HNMR (284 KB) RP-HPLC (237 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. [Content Brief]