2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. Gly-Gly-Phe-Gly-NH-O-CO-Exatecan

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a Drug-Linker Conjugates for ADC, consiting of an ADC linker and Exatecan (HY-13631) (topoisomerase I inhibitor). Gly-Gly-Phe-Gly-NH-O-CO-Exatecan can be used for ADC molecues synthesis.

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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan Chemical Structure

CAS No. : 1599440-12-6

Size Prix Stock Quantité
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtenir un devis  
500 mg   Obtenir un devis  

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Other Forms of Gly-Gly-Phe-Gly-NH-O-CO-Exatecan:

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan Related Antibodies

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Description

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a Drug-Linker Conjugates for ADC, consiting of an ADC linker and Exatecan (HY-13631) (topoisomerase I inhibitor). Gly-Gly-Phe-Gly-NH-O-CO-Exatecan can be used for ADC molecues synthesis.

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan Related Antibodies
Masse moléculaire

840.85

Formule

C42H45FN8O10
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CC1=C(F)C=C2C3=C1CC[C@H](NC(COCNC(CNC([C@H](CC4=CC=CC=C4)NC(CNC(CN)=O)=O)=O)=O)=O)C3=C5C(C(N6C5)=CC([C@@](O)(CC)C(OC7)=O)=C7C6=O)=N2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvant et solubilité
In Vitro: 

DMSO : 100 mg/mL (118.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1893 mL 5.9464 mL 11.8927 mL
5 mM 0.2379 mL 1.1893 mL 2.3785 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculateur de molarité

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Pureté et documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1893 mL 5.9464 mL 11.8927 mL 29.7318 mL
5 mM 0.2379 mL 1.1893 mL 2.3785 mL 5.9464 mL
10 mM 0.1189 mL 0.5946 mL 1.1893 mL 2.9732 mL
15 mM 0.0793 mL 0.3964 mL 0.7928 mL 1.9821 mL
20 mM 0.0595 mL 0.2973 mL 0.5946 mL 1.4866 mL
25 mM 0.0476 mL 0.2379 mL 0.4757 mL 1.1893 mL
30 mM 0.0396 mL 0.1982 mL 0.3964 mL 0.9911 mL
40 mM 0.0297 mL 0.1487 mL 0.2973 mL 0.7433 mL
50 mM 0.0238 mL 0.1189 mL 0.2379 mL 0.5946 mL
60 mM 0.0198 mL 0.0991 mL 0.1982 mL 0.4955 mL
80 mM 0.0149 mL 0.0743 mL 0.1487 mL 0.3716 mL
100 mM 0.0119 mL 0.0595 mL 0.1189 mL 0.2973 mL
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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan1599440-12-6Drug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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Nom du produit:
Gly-Gly-Phe-Gly-NH-O-CO-Exatecan
Cat. No.:
HY-13631M
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