Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride

Cat. No.: HY-13631F Purity: 99.78%: FAQs
Data Sheet SDS COA Handling Instructions

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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research.

For research use only. We do not sell to patients.

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 500	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 800	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1440	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 2050	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 2900	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride:

Deruxtecan In-stock
Exatecan mesylate dihydrate Get quote

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Biological Activity
Purity & Documentation
References
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Description	Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research^[1]^[2].
Molecular Weight	877.31
Formula	C₄₂H₄₆ClFN₈O₁₀
Appearance	Solid
Color	Off-white to yellow
SMILES	CC1=C(F)C=C2C3=C1CC[C@H](NC(COCNC(CNC([C@H](CC4=CC=CC=C4)NC(CNC(CN)=O)=O)=O)=O)=O)C3=C5C(C(N6C5)=CC([C@@](O)(CC)C(OC7)=O)=C7C6=O)=N2.[H]Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Purity & Documentation	Purity: 99.78% Select Batch: Data Sheet (274 KB) SDS (0 KB) COA (259 KB) HNMR (295 KB) RP-HPLC (192 KB) LCMS (102 KB) Handling Instructions (2659 KB)
References	[1]. Joto N, et al. DX-8951f, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant. Int J Cancer. 1997;72(4):680-686. [Content Brief] [2]. Thomas A, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016;17(6):e254-e262. [Content Brief]