Gly-Pro-pNA hydrochloride

Name: Gly-Pro-pNA hydrochloride
Brand: MedChemExpress
SKU: HY-119244
Rating: 4.5 (0 reviews)

製品番号: HY-119244 純度: 99.92%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

Gly-Pro-pNA hydrochloride is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA hydrochloride can be investigated as an experimental antidiabetic agent.

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Gly-Pro-pNA hydrochloride 構造式

CAS 番号 : 103213-34-9

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 44	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 44	在庫あり	Estimated Time of Arrival: December 31
Solid
5 mg	$40	在庫あり	Estimated Time of Arrival: December 31
10 mg	$65	在庫あり	Estimated Time of Arrival: December 31
25 mg	$130	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Dipeptidyl Peptidase アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

DPP-1 DPP-2 DPP-4 DPP-8 DPP-9

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

体外実験

Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

328.76

分子式

C₁₃H₁₇ClN₄O₄

CAS 番号

103213-34-9

Appearance

Solid

Color

White to yellow

SMILES

O=C(N1CCC[C@H]1C(NC2=CC=C(C=C2)[N+]([O-])=O)=O)CN.Cl

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (304.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 50 mg/mL (152.09 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0417 mL	15.2087 mL	30.4173 mL
5 mM	0.6083 mL	3.0417 mL	6.0835 mL
10 mM	0.3042 mL	1.5209 mL	3.0417 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.92%

Select Batch:

データシート (275 KB) SDS (393 KB)

COA (253 KB) HNMR (264 KB) LCMS (91 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Kim YB, et al. Mechanism of Gly-Pro-pNA cleavage catalyzed by dipeptidyl peptidase-IV and its inhibition by saxagliptin (BMS-477118). Arch Biochem Biophys. 2006;445(1):9-18. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	3.0417 mL	15.2087 mL	30.4173 mL	76.0433 mL
	5 mM	0.6083 mL	3.0417 mL	6.0835 mL	15.2087 mL
	10 mM	0.3042 mL	1.5209 mL	3.0417 mL	7.6043 mL
	15 mM	0.2028 mL	1.0139 mL	2.0278 mL	5.0696 mL
	20 mM	0.1521 mL	0.7604 mL	1.5209 mL	3.8022 mL
	25 mM	0.1217 mL	0.6083 mL	1.2167 mL	3.0417 mL
	30 mM	0.1014 mL	0.5070 mL	1.0139 mL	2.5348 mL
	40 mM	0.0760 mL	0.3802 mL	0.7604 mL	1.9011 mL
	50 mM	0.0608 mL	0.3042 mL	0.6083 mL	1.5209 mL
	60 mM	0.0507 mL	0.2535 mL	0.5070 mL	1.2674 mL
	80 mM	0.0380 mL	0.1901 mL	0.3802 mL	0.9505 mL
	100 mM	0.0304 mL	0.1521 mL	0.3042 mL	0.7604 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.