2. Neuronal Signaling
  3. Monoamine Oxidase
  4. hMAO-B-IN-5

hMAO-B-IN-5 (Compound B15) is a potent, selective and reversible human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 of 120 nM and a Ki of 33 nM. hMAO-B-IN-5 can be used in the research of neurodegenerative diseases.

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hMAO-B-IN-5

hMAO-B-IN-5 화학구조

CAS No. : 358343-63-2

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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hMAO-B-IN-5 Related Antibodies

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MAO-A MAO-B

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제품 설명

hMAO-B-IN-5 (Compound B15) is a potent, selective and reversible human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 of 120 nM and a Ki of 33 nM. hMAO-B-IN-5 can be used in the research of neurodegenerative diseases[1].

IC50 & Target[1]

hMAO-B

120 nM (IC50)

hMAO-B

33 nM (Ki)

hMAO-A

34512 nM (IC50)

분자량

358.43

화학식

C24H22O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(OCC)C=C1)/C=C/C2=CC=C(OCC3=CC=CC=C3)C=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도
In Vitro: 

DMSO : 50 mg/mL (139.50 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7899 mL 13.9497 mL 27.8995 mL
5 mM 0.5580 mL 2.7899 mL 5.5799 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7899 mL 13.9497 mL 27.8995 mL 69.7486 mL
5 mM 0.5580 mL 2.7899 mL 5.5799 mL 13.9497 mL
10 mM 0.2790 mL 1.3950 mL 2.7899 mL 6.9749 mL
15 mM 0.1860 mL 0.9300 mL 1.8600 mL 4.6499 mL
20 mM 0.1395 mL 0.6975 mL 1.3950 mL 3.4874 mL
25 mM 0.1116 mL 0.5580 mL 1.1160 mL 2.7899 mL
30 mM 0.0930 mL 0.4650 mL 0.9300 mL 2.3250 mL
40 mM 0.0697 mL 0.3487 mL 0.6975 mL 1.7437 mL
50 mM 0.0558 mL 0.2790 mL 0.5580 mL 1.3950 mL
60 mM 0.0465 mL 0.2325 mL 0.4650 mL 1.1625 mL
80 mM 0.0349 mL 0.1744 mL 0.3487 mL 0.8719 mL
100 mM 0.0279 mL 0.1395 mL 0.2790 mL 0.6975 mL
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hMAO-B-IN-5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hMAO-B-IN-5358343-63-2Monoamine OxidaseMAOhMAO-Bblood-brain barrierneurodegenerative diseasesInhibitorinhibitorinhibit

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상품명:
hMAO-B-IN-5
Cat. No.:
HY-W083062
수량:
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