2. Lipids
  3. Isotope-Labeled Lipids
  4. Isotope-Labeled Sphingolipids
  5. Isotope-Labeled Sphingoid Bases

Isotope-Labeled Sphingoid Bases

Isotope-Labeled Sphingoid Bases (13):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-101047S
    D-erythro-Sphingosine-d7 1246304-34-6 99.9%
    D-erythro-Sphingosine-d7 is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator.
    D-erythro-Sphingosine-d<sub>7</sub>
  • HY-108496S
    Sphingosine-1-phosphate-d7 2260670-15-1 99.9%
    Sphingosine-1-phosphate-d7 is the deuterium labeled Sphingosine-1-phosphate. Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12.?Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids.
    Sphingosine-1-phosphate-d<sub>7</sub>
  • HY-W019838S
    D-Erythro-dihydrosphingosine-d7 1246304-35-7 99.00%
    D-Erythro-dihydrosphingosine-d7 is the deuterium labeled D-Erythro-dihydrosphingosine. D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.
    D-Erythro-dihydrosphingosine-d<sub>7</sub>
  • HY-13626S
    Spisulosine-d3 1246298-31-6 99.0%
    Spisulosine-d3 (ES-285-d3) is deuterium labeled Spisulosine (HY-13626). Spisulosine is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation. Spisulosine induces apoptosis in PC-3 and LNCaP cells.
    Spisulosine-d<sub>3</sub>
  • HY-132187S1
    Sphingosylphosphorylcholine-d7 2260670-14-0 99.90%
    Sphingosylphosphorylcholine-d7 is the deuterium labeled Sphingosylphosphorylcholine (HY-132187).
    Sphingosylphosphorylcholine-d<sub>7</sub>
  • HY-101047S1
    D-erythro-Sphingosine-13C2,d2 2692623-81-5
    D-erythro-Sphingosine-13C2,d2 is a deuterated labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator.
    D-erythro-Sphingosine-<sup>13</sup>C<sub>2</sub>,d<sub>2</sub>
  • HY-N6726S1
    Fumonisin B3-13C34-1 1217494-88-6
    Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma.
    Fumonisin B3-<sup>13</sup>C<sub>34</sub>-1
  • HY-N6726S
    Fumonisin B3-13C34 2819816-90-3
    Fumonisin B3-13C34 is the 13C labeled Fumonisin B3 (HY-N6726). Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma.
    Fumonisin B3-<sup>13</sup>C<sub>34</sub>
  • HY-N6723S
    Fumonisin B2-13C34 1217481-36-1
    Fumonisin B2-13C34 is the 13C labeled Fumonisin B2 (HY-N6723). Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis.
    Fumonisin B2-<sup>13</sup>C<sub>34</sub>
  • HY-N6719S
    Fumonisin B1-13C34 1217458-62-2 98.5%
    Fumonisin B1-13C34 is the 13C labeled Fumonisin B1 (HY-N6719). Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin.
    Fumonisin B1-<sup>13</sup>C<sub>34</sub>
  • HY-132187S
    Sphingosylphosphorylcholine-d9 2315262-28-1 99.0%
    Sphingosylphosphorylcholine-d9 is deuterium labeled Sphingosylphosphorylcholine.
    Sphingosylphosphorylcholine-d<sub>9</sub>
  • HY-113116S
    Sphinganine 1-phosphate-d7 2315262-23-6
    Sphinganine 1-phosphate-d7 is deuterium labeled Sphinganine 1-phosphate. Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiologic
    Sphinganine 1-phosphate-d<sub>7</sub>
  • HY-108491S
    N,N-Dimethylsphingosine-13C2
    N,N-Dimethylsphingosine-13C2 is the 13C-labeled N,N-Dimethylsphingosine (HY-108491). N,N-Dimethylsphingosine is a sphingosine kinase inhibitor. N,N-Dimethylsphingosine binds competitively to sphingosine kinase and blocks the conversion of sphingosine to sphingosine-1-phosphate. N,N-Dimethylsphingosine inhibits sphingosine-1-phosphate release and aggregation of platelets, and also exerts pro-apoptotic effects by resetting ceramide/sphingosine-1-phosphate homeostasis. N,N-Dimethylsphingosine can be used in cancer-related research.
    N,N-Dimethylsphingosine-<sup>13</sup>C<sub>2</sub>